General Information of the Compound
Compound ID
CP0341353
Compound Name
(S)-2-(2-(3-(2,6-dichlorophenyl)ureido)-2-naphthamido)succinic acid
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Structure
Formula
C22H17Cl2N3O6
Molecular Weight
490.299
Canonical SMILES
OC(=O)C[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cccc1Cl)C(O)=O
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InChI
InChI=1S/C22H17Cl2N3O6/c23-14-6-3-7-15(24)19(14)27-22(33)26-16-9-12-5-2-1-4-11(12)8-13(16)20(30)25-17(21(31)32)10-18(28)29/h1-9,17H,10H2,(H,25,30)(H,28,29)(H,31,32)(H2,26,27,33)/t17-/m0/s1
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InChIKey
BWTSVKZIQSCLAT-KRWDZBQOSA-N
Physicochemical Property
logP
4.4483
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
144.83
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
4
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24894011
SID: 53776622
ChEMBL ID
CHEMBL471372
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01561, Glycogen phosphorylase, liver form
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 640 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 230 nM