General Information of the Compound
Compound ID
CP0128788
Compound Name
(S)-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphthamido)succinic acid
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Structure
Formula
C24H23N3O6
Molecular Weight
449.463
Canonical SMILES
Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N[C@@H](CC(O)=O)C(O)=O
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InChI
InChI=1S/C24H23N3O6/c1-13-6-5-7-14(2)21(13)27-24(33)26-18-11-16-9-4-3-8-15(16)10-17(18)22(30)25-19(23(31)32)12-20(28)29/h3-11,19H,12H2,1-2H3,(H,25,30)(H,28,29)(H,31,32)(H2,26,27,33)/t19-/m0/s1
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InChIKey
XLRNOBHCDGERDN-IBGZPJMESA-N
Physicochemical Property
logP
3.75834
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
144.83
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
4
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44560979
ChEMBL ID
CHEMBL511305
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01561, Glycogen phosphorylase, liver form
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 120 nM