General Information of the Compound
Compound ID
CP0317035
Compound Name
2-(3-(3-mesitylureido)-2-naphthamido)-2-(1,4-dioxaspiro[4.5]decan-8-yl)acetic acid
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Structure
Formula
C31H35N3O6
Molecular Weight
545.636
Canonical SMILES
Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC(C2CCC3(CC2)OCCO3)C(O)=O)c(C)c1
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InChI
InChI=1S/C31H35N3O6/c1-18-14-19(2)26(20(3)15-18)34-30(38)32-25-17-23-7-5-4-6-22(23)16-24(25)28(35)33-27(29(36)37)21-8-10-31(11-9-21)39-12-13-40-31/h4-7,14-17,21,27H,8-13H2,1-3H3,(H,33,35)(H,36,37)(H2,32,34,38)
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InChIKey
PXLOSBDARKDVEX-UHFFFAOYSA-N
Physicochemical Property
logP
5.52536
Rotatable Bonds
6
Heavy Atom Count
40
Polar Areas
125.99
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
5
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11592021
SID: 16694499
ChEMBL ID
CHEMBL475449
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01561, Glycogen phosphorylase, liver form
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 2053 nM
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