| Compound ID |
Compound Name |
Compound Formula |
|
CP0553564
|
6-[2-ethoxyethyl-(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]-3H-1,3-benzothiazol-2-one
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|
C19H18N4O2S2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0365088
|
6-[(1S)-1-(1-pyridin-2-ylpyrazol-3-yl)ethyl]-3H-1,3-benzothiazol-2-one
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|
C17H14N4OS
|
3
|
| 1 |
IC50 = 50.9 nM
|
|
|
| 2 |
IC50 = 9260 nM
|
|
|
| 3 |
IC50 = 83300 nM
|
|
|
|
CP0466942
|
6-[(1S)-1-[1-(5-fluoropyridin-2-yl)pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one
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|
C17H13FN4OS
|
2
|
| 1 |
IC50 = 53.6 nM
|
|
|
| 2 |
IC50 = 83300 nM
|
|
|
|
CP0346960
|
N-(1H-indazol-5-yl)-N-[(1-methylpyrazol-3-yl)methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine
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|
C20H17N7S
|
2
|
| 1 |
IC50 = 53.9 nM
|
|
|
| 2 |
IC50 = 83300 nM
|
|
|
|
CP0466863
|
6-[(1S)-1-[1-[5-(2-hydroxyethyl)pyridin-2-yl]pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one
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|
C19H18N4O2S
|
3
|
| 1 |
IC50 = 61.6 nM
|
|
|
| 2 |
IC50 = 25700 nM
|
|
|
| 3 |
IC50 = 83300 nM
|
|
|
|
CP0459837
|
6-[(1S)-1-[1-[5-(2-hydroxyethoxy)pyridin-2-yl]pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one
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|
C19H18N4O3S
|
3
|
| 1 |
IC50 = 65.3 nM
|
|
|
| 2 |
IC50 = 68500 nM
|
|
|
| 3 |
IC50 = 83300 nM
|
|
|
|
CP0466941
|
6-[methyl-(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]-3H-1,3-benzothiazol-2-one
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|
C16H12N4OS2
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
IC50 > 83300 nM
|
|
|
|
CP0459836
|
6-[1-(1-pyridin-2-ylpyrazol-3-yl)ethyl]-3H-1,3-benzothiazol-2-one
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|
C17H14N4OS
|
2
|
| 1 |
IC50 = 122 nM
|
|
|
| 2 |
IC50 = 83300 nM
|
|
|
|
CP0459838
|
N-(1H-indazol-5-yl)-N-methyl-4-pyridin-2-yl-1,3-thiazol-2-amine
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|
C16H13N5S
|
2
|
| 1 |
IC50 = 147 nM
|
|
|
| 2 |
IC50 > 83300 nM
|
|
|
|
CP0553972
|
6-[(1S)-1-[1-[5-(3-hydroxy-3-methylbutyl)pyridin-2-yl]pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one
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|
C22H24N4O2S
|
2
|
| 1 |
IC50 = 160 nM
|
|
|
| 2 |
IC50 = 9260 nM
|
|
|
|
CP0459839
|
CHEBI:71013
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|
C23H15N3O
|
5
|
| 1 |
IC50 = 243 nM
|
|
|
| 2 |
IC50 = 485 nM
|
|
|
| 3 |
IC50 = 623 nM
|
|
|
| 4 |
IC50 = 1180 nM
|
|
|
| 5 |
IC50 = 6510 nM
|
|
|
|
CP0365087
|
N-methyl-N-(1-pyridin-2-ylpyrazol-3-yl)-1H-indazol-5-amine
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|
C16H14N6
|
2
|
| 1 |
IC50 = 353 nM
|
|
|
| 2 |
IC50 > 83300 nM
|
|
|
|
CP0459841
|
6-[(1R)-1-(1-pyridin-2-ylpyrazol-3-yl)ethyl]-3H-1,3-benzothiazol-2-one
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|
C17H14N4OS
|
3
|
| 1 |
IC50 = 615 nM
|
|
|
| 2 |
IC50 = 9260 nM
|
|
|
| 3 |
IC50 = 83300 nM
|
|
|
|
CP0527396
|
6-[(1R)-1-[1-[5-(2-hydroxyethoxy)pyridin-2-yl]pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one
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|
C19H18N4O3S
|
2
|
| 1 |
IC50 = 1790 nM
|
|
|
| 2 |
IC50 = 9260 nM
|
|
|
|
CP0466864
|
6-[(1R)-1-[1-[5-(2-hydroxyethyl)pyridin-2-yl]pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one
Show/Hide
|
C19H18N4O2S
|
2
|
| 1 |
IC50 = 2820 nM
|
|
|
| 2 |
IC50 = 9260 nM
|
|
|
|
CP0538961
|
4-[methyl-(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]phenol
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|
C15H13N3OS
|
2
|
| 1 |
IC50 = 2970 nM
|
|
|
| 2 |
IC50 > 83300 nM
|
|
|
