Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[(1S)-1-[1-[5-(2-hydroxyethyl)pyridin-2-yl]pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one
    Show/Hide
 PubChem ID
CID: 118536551
Canonical SMILES
C[C@H](c1ccn(n1)-c1ccc(CCO)cn1)c1ccc2[nH]c(=O)sc2c1
    Show/Hide
Compound Formula C19H18N4O2S
Compound Structure
Protein Name
 Protein Info 
Glutamate receptor 1
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42261
Gene Name
GRIA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000470 CHO-S
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 61.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 25700 nM
   TI
   LI
   LO
   TS
3
IC50 = 83300 nM
   TI
   LI
   LO
   TS