Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1H-indazol-5-yl)-N-[(1-methylpyrazol-3-yl)methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine
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 PubChem ID
CID: 127048931
Canonical SMILES
Cn1ccc(CN(c2nc(cs2)-c2ccccn2)c2ccc3[nH]ncc3c2)n1
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Compound Formula C20H17N7S
Compound Structure
Protein Name
 Protein Info 
Glutamate receptor 1
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42261
Gene Name
GRIA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000470 CHO-S
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 53.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 83300 nM
   TI
   LI
   LO
   TS