Brief Information of the Compound and Protein
Compound Name
CHEBI:71013
    Show/Hide
PubChem ID
CID: 9924495
SID: 14896254
Canonical SMILES
O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N
    Show/Hide
Compound Formula C23H15N3O
Compound Structure
Protein Name
Glutamate receptor 1
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42261
Gene Name
GRIA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000470 CHO-S Cricetulus griseus (Chinese hamster)  5
1
IC50 = 243 nM
   TI
   LI
   LO
   TS
2
IC50 = 485 nM
   TI
   LI
   LO
   TS
3
IC50 = 623 nM
   TI
   LI
   LO
   TS
4
IC50 = 1180 nM
   TI
   LI
   LO
   TS
5
IC50 = 6510 nM
   TI
   LI
   LO
   TS