General Information of the Compound
| Compound ID |
CP0459839
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| Compound Name |
CHEBI:71013
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| Synonyms |
2-(2-oxo-1-phenyl-5-pyridin-2-yl-pyridin-3-yl)benzonitrile
3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
E 2007
E-2007
Perampanel
Perampanel (USAN)
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| Structure |
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| Formula |
C23H15N3O
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| Molecular Weight |
349.393
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| Canonical SMILES |
O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N
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| InChI |
InChI=1S/C23H15N3O/c24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19/h1-14,16H
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| InChIKey |
PRMWGUBFXWROHD-UHFFFAOYSA-N
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| CAS |
380917-97-5
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03542, Glutamate receptor 1
Clinical Information about the Compound
Drug 1 ( E-2007 )
| Drug Name | E-2007 | ||
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| Company | Eisai Co. Ltd. | ||
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