Brief Information of the Compound and Protein
Compound Name
6-[(1R)-1-(1-pyridin-2-ylpyrazol-3-yl)ethyl]-3H-1,3-benzothiazol-2-one
    Show/Hide
PubChem ID
CID: 127048574
Canonical SMILES
C[C@@H](c1ccn(n1)-c1ccccn1)c1ccc2[nH]c(=O)sc2c1
    Show/Hide
Compound Formula C17H14N4OS
Compound Structure
Protein Name
Glutamate receptor 1
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42261
Gene Name
GRIA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000470 CHO-S Cricetulus griseus (Chinese hamster)  3
1
IC50 = 615 nM
   TI
   LI
   LO
   TS
2
IC50 = 9260 nM
   TI
   LI
   LO
   TS
3
IC50 = 83300 nM
   TI
   LI
   LO
   TS