| Compound ID |
Compound Name |
Compound Formula |
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
Show/Hide
|
C10H12N2O
|
2
|
| 1 |
EC50 = 4.67 nM
|
|
|
| 2 |
Ki = 5.012 nM
|
|
|
|
CP0056783
|
2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetrahydro-5-naphthalenyloxy)hexyloxy]-1,2,3,4-tetrahydro-2-naphthalenamine
Show/Hide
|
C38H60N2O2
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0479139
|
1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
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|
C27H30N4O
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0308736
|
3-[3-(4-Benzyl-4-fluoro-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
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|
C25H28FN5
|
2
|
| 1 |
EC50 = 66 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0101123
|
3-[3-(4-Benzyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
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|
C25H29N5
|
2
|
| 1 |
EC50 = 120 nM
|
|
|
| 2 |
IC50 = 19 nM
|
|
|
|
CP0658701
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
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|
C18H23ClN2S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0504542
|
6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
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|
C26H30N4O
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
|
CP0037227
|
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
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|
C16H25NO
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
|
CP0421403
|
3-{3-[4-Fluoro-4-(2-trifluoromethyl-benzyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
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|
C26H27F4N5
|
2
|
| 1 |
EC50 = 290 nM
|
|
|
| 2 |
IC50 = 14 nM
|
|
|
|
CP0386021
|
6-chloro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
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|
C26H27ClN4O
|
1
|
| 1 |
EC50 = 316.23 nM
|
|
|
|
CP0406077
|
1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
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|
C27H32N4O
|
1
|
| 1 |
EC50 = 398.11 nM
|
|
|
|
CP0136962
|
3-(3-{4-[2-(3-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
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|
C25H29FN6
|
3
|
| 1 |
EC50 = 430 nM
|
|
|
| 2 |
IC50 = 72 nM
|
|
|
| 3 |
IC50 = 75 nM
|
|
|
|
CP0404530
|
3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piperidin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
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|
C26H29F2N5
|
2
|
| 1 |
EC50 = 440 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0190295
|
3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
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|
C25H28FN5
|
2
|
| 1 |
EC50 = 450 nM
|
|
|
| 2 |
IC50 = 62 nM
|
|
|
|
CP0406078
|
6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
EC50 = 501.19 nM
|
|
|
|
CP0498039
|
3-{3-[4-Fluoro-4-(2-phenyl-propyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C27H32FN5
|
2
|
| 1 |
EC50 = 510 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
|
CP0395013
|
3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
EC50 = 810 nM
|
|
|
|
CP0376606
|
Benzyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
|
3
|
| 1 |
EC50 = 1400 nM
|
|
|
| 2 |
IC50 = 140 nM
|
|
|
| 3 |
IC50 = 145 nM
|
|
|
|
CP0497439
|
3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
2
|
| 1 |
EC50 = 1500 nM
|
|
|
| 2 |
IC50 = 280 nM
|
|
|
|
CP0395029
|
3-(2-Fluoro-3-{4-[2-(4-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
2
|
| 1 |
EC50 = 1700 nM
|
|
|
| 2 |
IC50 = 310 nM
|
|
|
|
CP0487478
|
3-{2,2-Difluoro-3-[4-(2-phenyl-propyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
2
|
| 1 |
EC50 = 5100 nM
|
|
|
| 2 |
IC50 = 1800 nM
|
|
|
|
CP0061753
|
1-NP
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|
C14H16N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0468024
|
3-[3-(4-Benzyloxy-piperidin-1-yl)-2,2-difluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H27F2N5O
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 1000 nM
|
|
|
|
CP0056779
|
1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthyloxy]ethane
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|
C32H38N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0448973
|
3-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C21H24N8
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0438469
|
N,N-dimethyl-2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethanamine
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|
C14H17N5
|
2
|
| 1 |
IC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 1.4 nM
|
|
|
|
CP0403825
|
N-[3-[[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]methyl]phenyl]acetamide
Show/Hide
|
C26H31N7O
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0448243
|
3-[2-((S)-2-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0395010
|
3-{3-[4-Fluoro-4-(2-fluoro-benzyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H27F2N5
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0504202
|
N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]pyridin-2-amine
Show/Hide
|
C24H29N7
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0502206
|
3-(2-Azetidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C15H17N5
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0498564
|
3-{3-[4-Fluoro-4-(3-fluoro-benzyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H27F2N5
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0393197
|
1-Methyl-3-phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-urea
Show/Hide
|
C27H33N7O
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0542475
|
3-(3-Morpholin-4-yl-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C17H21N5O
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0357622
|
3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H28N6
|
2
|
| 1 |
IC50 = 8.1 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0392525
|
N-[4-[[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]methyl]phenyl]acetamide
Show/Hide
|
C28H35N7O
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0430876
|
N-[4-[(1R)-1-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]ethyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0377606
|
N-[4-[(1S)-1-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]ethyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0460899
|
2-Phenyl-2-{4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-1-yl}-ethanol
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0005653
|
(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
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|
C14H21N3O2S
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
| 3 |
IC50 = 16 nM
|
|
|
|
CP0499516
|
N-methyl-N-[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C25H30N6O2S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0496271
|
N-benzyl-N-[[(3R)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]acetamide
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0406034
|
N-(furan-3-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C22H26N6O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0499480
|
(R)-N*2*,N*2*-Dimethyl-1-phenyl-N*1*-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-ethane-1,2-diamine
Show/Hide
|
C28H37N7
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0501149
|
(3S,4S)-N-benzyl-3-fluoro-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C26H31FN6
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0395405
|
3-{3-[4-(1-Phenyl-ethyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H30N6
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0454869
|
3-[3-(4-Phenyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H26N6
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0406225
|
((R)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C27H34N6
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0487078
|
3-(3-Piperidin-1-yl-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C18H23N5
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0402357
|
Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-2-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0446541
|
3-(3-{4-Fluoro-4-[2-(2-fluoro-phenyl)-ethyl]-piperidin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29F2N5
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0438472
|
N-methyl-2-phenyl-2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]ethanamine
Show/Hide
|
C26H33N7
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0479230
|
N-methyl-N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C26H32N6O2S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0405279
|
1-Benzyl-4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazine-2-thione
Show/Hide
|
C24H26N6S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0438815
|
3-[3-(4-Pyridin-2-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0448900
|
3-[3-(4-Furan-2-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C22H26N6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0441753
|
4-(3,3-Dimethyl-piperidin-1-ylmethyl)-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C26H38N6O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0375167
|
N-(furan-2-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C22H26N6O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0448268
|
3-{3-[4-(4-Fluoro-benzyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27FN6
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0377816
|
3-[3-(4-Pyridin-3-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0410485
|
3-[3-(4-Pyridin-4-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0375959
|
N-[4-[[methyl-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]amino]methyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0405595
|
N-methyl-N-(4-methylpent-3-enyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C25H36N6
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0439877
|
N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C28H34N6
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0421330
|
3-(3-{4-Fluoro-4-[2-(4-fluoro-phenyl)-ethyl]-piperidin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29F2N5
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0405735
|
4-[(Cyclohexylmethyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C27H40N6O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0494812
|
4-[(Cyclopropylmethyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C24H34N6O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0437579
|
Benzyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C27H34N6
|
2
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
|
CP0407101
|
3-[3-(4-Furan-3-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C22H26N6O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0372894
|
3-(2-Pyrrolidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C16H19N5
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
IC50 = 30.2 nM
|
|
|
|
CP0500771
|
Benzyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0376344
|
N-[4-[[[4-hydroxy-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]methyl]phenyl]acetamide
Show/Hide
|
C28H35N7O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0511195
|
4-[(Isobutyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C24H36N6O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0504140
|
4-Benzyl-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0398518
|
Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
2
|
| 1 |
IC50 = 32 nM
|
|
|
| 2 |
IC50 = 33 nM
|
|
|
|
CP0511265
|
3-[3-((R)-3-Benzyloxymethyl-pyrrolidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0483398
|
(S)-2-Phenyl-2-({1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amino)-ethanol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0474635
|
((R)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0373772
|
N-methyl-N-(thiophen-3-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H30N6S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0468110
|
3-{3-[4-(1H-Imidazol-2-ylmethyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C21H26N8
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0079840
|
Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C24H28N6
|
2
|
| 1 |
IC50 = 37 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
|
CP0123953
|
(1-Methyl-1-phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0420921
|
4-Acetylamino-N-methyl-N-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-benzamide
Show/Hide
|
C29H35N7O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0030068
|
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0382892
|
N-methyl-N-(3-methylbut-2-enyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H34N6
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0378028
|
((S)-1-Phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0483511
|
N-[4-[[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]methyl]phenyl]acetamide
Show/Hide
|
C27H33N7O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0377777
|
3-{3-[4-(2-Phenyl-propyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0453397
|
3-[3-(4-{2-[4-(3-Methyl-[1,2,4]oxadiazol-5-yl)-phenyl]-ethyl}-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C28H32N8O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0438357
|
3-(3-{4-[2-(3,5-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0496894
|
4-(Benzylamino-methyl)-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C26H32N6O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0464807
|
Benzyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C24H28N6
|
2
|
| 1 |
IC50 = 47 nM
|
|
|
| 2 |
IC50 = 50 nM
|
|
|
|
CP0377135
|
(1R,2R)-1-Phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-2-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0374965
|
N-(pyridin-2-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0415642
|
3-[3-(4-Fluoro-4-phenethyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30FN5
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0056703
|
(S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin-1-yl]-ethyl}-1H-indol-5-ylmethyl)-oxazolidin-2-one
Show/Hide
|
C26H32N4O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0115159
|
(S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-methyl]-pyrrolidin-1-yl}-ethyl)-1H-indol-5-ylmethyl]-oxazolidin-2-one
Show/Hide
|
C27H34N4O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0395348
|
4-{[(Pyridin-2-ylmethyl)-amino]-methyl}-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C25H31N7O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0511371
|
N-[4-[[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]methyl]phenyl]acetamide
Show/Hide
|
C26H31N7O
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0437770
|
4-[(Cyclopropylmethyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C23H32N6O
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0449271
|
((S)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C27H34N6
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0511172
|
Benzyl-methyl-{(S)-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0410463
|
3-{3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27ClN6
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0392444
|
N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C25H30N6O2S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0424644
|
4-{[(2,2-Dimethyl-propyl)-methyl-amino]-methyl}-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C25H38N6O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0041353
|
C-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin-1-yl]-ethyl}-1H-indol-5-yl)-N-methyl-methanesulfonamide
Show/Hide
|
C24H32N4O2S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0467572
|
N-(pyridin-3-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0502201
|
1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamine
Show/Hide
|
C18H24N6
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0460829
|
(4-Methanesulfonyl-benzyl)-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C28H36N6O2S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0514551
|
N-[4-[2-[methyl-[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0429012
|
(S)-4-[3-(2-{(S)-3-[(Benzyl-methyl-amino)-methyl]-pyrrolidin-1-yl}-ethyl)-1H-indol-5-ylmethyl]-3-methyl-oxazolidin-2-one
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0415084
|
(S)-2-(Methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amino)-2-phenyl-ethanol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0381322
|
1-{1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C25H27N7O
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0375941
|
((R)-1-Phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0483598
|
N-(pyridin-2-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H29N7
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0377018
|
N-[(2R)-2-phenyl-2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]methanesulfonamide
Show/Hide
|
C27H35N7O2S
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0404728
|
N-(furan-3-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C23H28N6O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0468111
|
1-Phenethyl-4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-2-one
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0404430
|
(R)-2-Phenyl-2-({1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amino)-ethanol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0437805
|
But-2-ynyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C23H30N6
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0448062
|
4-[(2-Methyl-benzylamino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0384114
|
3-(3-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
2
|
| 1 |
IC50 = 83 nM
|
|
|
| 2 |
IC50 = 98 nM
|
|
|
|
CP0502188
|
4-[(2,2-Dimethyl-propylamino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C24H36N6O
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0409861
|
(R)-N-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propionamide
Show/Hide
|
C27H33N7O
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0480630
|
(R)-2-(Methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amino)-2-phenyl-ethanol
Show/Hide
|
C28H36N6O
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0418953
|
3-[2-((R)-3-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27N5O
|
2
|
| 1 |
IC50 = 85 nM
|
|
|
| 2 |
IC50 = 88 nM
|
|
|
|
CP0449242
|
3-{3-[4-(3-Phenyl-propyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0447863
|
N-[[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]aniline
Show/Hide
|
C23H26N6
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0449810
|
(1S)-N-methyl-1-phenyl-N-[[(3R)-1-[2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]ethanamine
Show/Hide
|
C27H34N6
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0405114
|
4-{[Methyl-(2-methyl-benzyl)-amino]-methyl}-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C28H36N6O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0502071
|
N-[(1R)-1-(4-fluorophenyl)-2-methoxyethyl]-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C27H33FN6O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0503355
|
N-(furan-2-ylmethyl)-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H30N6O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0374963
|
[(3R)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanol
Show/Hide
|
C17H21N5O
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0380443
|
(R)-1-[2-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ol
Show/Hide
|
C16H19N5O
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0383077
|
3-{3-[4-(2-Pyridin-3-yl-ethyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H29N7
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0420958
|
((S)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0514196
|
4-[(Benzyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0392708
|
2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0377784
|
3-(3-{4-[2-(2-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29FN6
|
2
|
| 1 |
IC50 = 98 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0430871
|
(R)-3-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0409363
|
N-[4-[[methyl-[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]methyl]phenyl]acetamide
Show/Hide
|
C28H35N7O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0466543
|
(R)-2-{1-[3-(5-Imidazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-2-phenyl-ethanol
Show/Hide
|
C27H33N5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0438471
|
N,N-dimethyl-2-phenyl-2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]acetamide
Show/Hide
|
C27H33N7O
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0375894
|
(R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H32N6O
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 114 nM
|
|
|
|
CP0406224
|
1-[3-(5-imidazol-1-yl-1H-indol-3-yl)propyl]-N-[(1R)-1-phenylethyl]piperidin-4-amine
Show/Hide
|
C27H33N5
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0442688
|
N-(pyridin-4-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0374169
|
3-(3-{4-[2-(4-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29FN6
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0376530
|
[(2R)-2-phenyl-2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl] carbamate
Show/Hide
|
C27H33N7O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0440490
|
Benzyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C25H30N6
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 125 nM
|
|
|
|
CP0327065
|
2-phenyl-N-[[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]ethanamine
Show/Hide
|
C25H30N6
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0438816
|
4-{4-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-1-ylmethyl}-benzonitrile
Show/Hide
|
C25H27N7
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0453637
|
(S)-3-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0376999
|
N-(pyridin-4-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H29N7
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0404804
|
N-methyl-N-(thiophen-2-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H30N6S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0420959
|
(4-Methanesulfonyl-benzyl)-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C27H34N6O2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0504032
|
N-(pyridin-3-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H29N7
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0508887
|
1-Methyl-3-phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-urea
Show/Hide
|
C26H31N7O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0429000
|
3-[2-((R)-3-Benzyloxy-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H25N5O
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0383076
|
3-(3-Piperazin-1-yl-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C17H22N6
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0377036
|
3-Phenyl-3-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0395135
|
(R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H31FN6O
|
2
|
| 1 |
IC50 = 150 nM
|
|
|
| 2 |
IC50 = 185 nM
|
|
|
|
CP0409378
|
(1R,2S)-1-Phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-2-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0378481
|
(S)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H32N6O
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0431656
|
(S)-2-Phenyl-2-({(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amino)-ethanol
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0447958
|
N-[4-[[[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methylamino]methyl]phenyl]acetamide
Show/Hide
|
C26H31N7O
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0372707
|
3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H30N6
|
2
|
| 1 |
IC50 = 166 nM
|
|
|
| 2 |
IC50 = 170 nM
|
|
|
|
CP0454584
|
N-[3-[2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]ethyl]phenyl]acetamide
Show/Hide
|
C27H33N7O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0509117
|
((R)-1-Methyl-2-phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C27H34N6
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0504203
|
N-[4-[2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]phenyl]acetamide
Show/Hide
|
C28H35N7O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0509615
|
(3S,4S)-3-fluoro-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
|
C26H28F4N6
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0392733
|
(1R,2R)-1-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0377296
|
N-(furan-3-ylmethyl)-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H30N6O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0418379
|
Benzyl-methyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-yl}-amine
Show/Hide
|
C24H28N6
|
2
|
| 1 |
IC50 = 209 nM
|
|
|
| 2 |
IC50 = 210 nM
|
|
|
|
CP0376627
|
(R)-2-(Methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amino)-2-phenyl-ethanol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0382929
|
((R)-2-Methoxy-1-phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0409041
|
(1S,2R)-1-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0845065
|
(R)-1-{(S)-1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-indan-2-ol
Show/Hide
|
C27H32N6O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0395040
|
Benzyl-{(3R,4S)-3-fluoro-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-methyl-amine
Show/Hide
|
C26H31FN6
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0415643
|
(3R,4S)-3-fluoro-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
|
C27H30F4N6
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0497734
|
(3S,4S)-3-fluoro-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
|
C27H30F4N6
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0502338
|
N-[1-(4-fluorophenyl)ethyl]-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C26H31FN6
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0406721
|
N-[4-[2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]ethyl]phenyl]acetamide
Show/Hide
|
C27H33N7O
|
2
|
| 1 |
IC50 = 251 nM
|
|
|
| 2 |
IC50 = 260 nM
|
|
|
|
CP0420915
|
N-(cyclopropylmethyl)-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C23H32N6
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0457220
|
N-methyl-1-[3-[3-[4-[[(1R)-1-phenylethyl]amino]piperidin-1-yl]propyl]-1H-indol-5-yl]methanesulfonamide
Show/Hide
|
C26H36N4O2S
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0376850
|
Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0506684
|
(R)-2-Phenyl-2-({(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amino)-ethanol
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0376560
|
3-[2-((S)-3-Benzyloxy-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H25N5O
|
1
|
| 1 |
IC50 = 275 nM
|
|
|
|
CP0406242
|
N-(2,3-dihydro-1H-inden-1-yl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C27H32N6
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0410759
|
5-[1,2,4]Triazol-4-yl-3-{3-[4-(4-trifluoromethyl-benzyl)-piperazin-1-yl]-propyl}-1H-indole
Show/Hide
|
C25H27F3N6
|
1
|
| 1 |
IC50 = 282 nM
|
|
|
|
CP0453504
|
1-Benzyl-4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-2-one
Show/Hide
|
C24H26N6O
|
1
|
| 1 |
IC50 = 282 nM
|
|
|
|
CP0499517
|
(S)-1-{(R)-1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-indan-2-ol
Show/Hide
|
C27H32N6O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0468023
|
(3R,4S)-3-fluoro-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
|
C26H28F4N6
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0395210
|
3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C17H22N6
|
2
|
| 1 |
IC50 = 304 nM
|
|
|
| 2 |
IC50 = 310 nM
|
|
|
|
CP0503514
|
((S)-1-Phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
|
CP0470678
|
3-[3-(4-Methyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C18H24N6
|
2
|
| 1 |
IC50 = 309 nM
|
|
|
| 2 |
IC50 = 430 nM
|
|
|
|
CP0464787
|
Allyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C22H30N6
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0509931
|
Allyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C20H26N6
|
1
|
| 1 |
IC50 = 325 nM
|
|
|
|
CP0401299
|
tert-butyl N-[[4-hydroxy-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]carbamate
Show/Hide
|
C24H34N6O3
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0565410
|
N-[4-[(1R)-1-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]phenyl]acetamide
Show/Hide
|
C28H35N7O
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0422756
|
1-(4-Benzyl-piperazin-1-yl)-3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propan-2-ol
Show/Hide
|
C24H28N6O
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0504688
|
3-(2-Fluoro-3-{4-[2-(2-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0404431
|
(R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H32N6O
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0376955
|
2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-[1,4']bipiperidinyl
Show/Hide
|
C29H36N6
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0420929
|
((R)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0431438
|
(S)-4-(3-{3-[4-((R)-2-Hydroxy-1-phenyl-ethylamino)-piperidin-1-yl]-propyl}-1H-indol-5-ylmethyl)-oxazolidin-2-one
Show/Hide
|
C28H36N4O3
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0496764
|
3-(2-Fluoro-3-{4-[2-(2-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0410106
|
3-(2-Fluoro-3-{4-[2-(4-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0425067
|
3-(2-Piperidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C17H21N5
|
2
|
| 1 |
IC50 = 568 nM
|
|
|
| 2 |
IC50 = 570 nM
|
|
|
|
CP0375911
|
Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 575 nM
|
|
|
|
CP0392837
|
3-[2-((R)-2-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 = 575 nM
|
|
|
|
CP0462723
|
3-[(2S)-2-fluoro-3-[4-[2-(3-fluorophenyl)ethyl]piperazin-1-yl]propyl]-5-(1,2,4-triazol-4-yl)-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0463038
|
3-[2-Fluoro-3-(4-phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29FN6
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
|
CP0393241
|
3-(2,2-Difluoro-3-{4-[2-(4-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29F3N6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0415184
|
N-[(1R)-1-(4-fluorophenyl)-2-methoxyethyl]-1-[3-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C28H35FN6O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0383146
|
Benzyl-{1-[2-fluoro-3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-methyl-amine
Show/Hide
|
C26H31FN6
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0409608
|
(R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
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C27H34N6O
|
1
|
| 1 |
IC50 = 1300 nM
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CP0422757
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3-[3-(4-Benzyl-piperidin-1-yl)-2,2-difluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H27F2N5
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1
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| 1 |
IC50 = 1300 nM
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CP0498565
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3-(2,2-Difluoro-3-{4-[2-(3-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H27F3N6
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1
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| 1 |
IC50 = 1600 nM
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CP0497440
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Benzyl-{1-[2,2-difluoro-3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-methyl-amine
Show/Hide
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C26H30F2N6
|
1
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| 1 |
IC50 = 2100 nM
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CP0431094
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3-[3-(4-Benzyloxy-piperidin-1-yl)-2-fluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H28FN5O
|
1
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| 1 |
IC50 = 3000 nM
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CP0453021
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4-Benzyl-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-2-one
Show/Hide
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C24H26N6O
|
1
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| 1 |
IC50 = 3900 nM
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CP0529312
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3-[4-(4-Methyl-piperazin-1-yl)-butyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C19H26N6
|
1
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| 1 |
IC50 = 5100 nM
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CP0504689
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3-[2,2-Difluoro-3-(4-phenethyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C26H29F2N5
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1
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| 1 |
IC50 = 5800 nM
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CP0055933
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3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
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C22H22FN3O3
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2
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| 1 |
IC50 = 6500 nM
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| 2 |
IC50 > 10000 nM
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CP0460034
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3-[2,2-Difluoro-3-(4-phenoxymethyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H27F2N5O
|
1
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| 1 |
IC50 = 7200 nM
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CP0068074
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine-3-carboxamide
Show/Hide
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C27H28N6O2
|
3
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| 1 |
Kd = 1.175 nM
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| 2 |
Ki = 0.7943 nM
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| 3 |
Ki = 1.585 nM
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CP0146099
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8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
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C26H29FN4O3
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1
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| 1 |
Ki = 0.1995 nM
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CP0218850
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H26N4O2
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3
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| 1 |
Ki = 0.1995 nM
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| 2 |
Ki = 0.5012 nM
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| 3 |
Ki = 251.19 nM
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CP0422491
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6-[2-[4-(2-phenylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C29H28N4O2
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1
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| 1 |
Ki = 0.3162 nM
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CP0397086
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6-[2-[4-(2-methyl-1H-indol-4-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C23H26N4O2
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1
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| 1 |
Ki = 0.3981 nM
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CP0427664
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5-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H25FN4O2
|
1
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| 1 |
Ki = 0.3981 nM
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CP0126585
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4-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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2
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| 1 |
Ki = 0.5012 nM
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| 2 |
Ki = 1.995 nM
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CP0412277
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6-[2-[4-(8-chloro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H25ClN4O2
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1
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| 1 |
Ki = 0.5012 nM
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CP0422492
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6-[2-[4-(7-chloro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H25ClN4O2
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1
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| 1 |
Ki = 0.5012 nM
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CP0104145
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N-cyclopropyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C30H32N6O2
|
1
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| 1 |
Ki = 0.5012 nM
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CP0040405
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N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]acetamide
Show/Hide
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C24H28N4O
|
1
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| 1 |
Ki = 0.5012 nM
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CP0648464
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Methyl(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)carbamate
Show/Hide
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C24H28N4O2
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1
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| 1 |
Ki = 0.5012 nM
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CP0397084
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6-[2-[4-(2,7-dimethylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 0.631 nM
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CP0397085
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6-[2-[4-(2-methylquinazolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C23H25N5O2
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1
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| 1 |
Ki = 0.631 nM
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CP0412307
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6-[2-[4-(2,2-dimethyl-3H-1-benzofuran-7-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H29N3O3
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1
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| 1 |
Ki = 0.631 nM
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CP0068073
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N,N-dimethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C29H32N6O2
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1
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| 1 |
Ki = 0.631 nM
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CP0260884
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N-cyclobutyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C31H34N6O2
|
1
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| 1 |
Ki = 0.631 nM
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CP0406079
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5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H28N4O
|
1
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| 1 |
Ki = 0.631 nM
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CP0372020
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8-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28FN3O3
|
1
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| 1 |
Ki = 0.7943 nM
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CP0377439
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4-ethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
|
C26H30N4O2
|
1
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| 1 |
Ki = 0.7943 nM
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CP0398940
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6-[2-[(1R,4R)-5-(2-methylquinolin-5-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H26N4O2
|
1
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| 1 |
Ki = 0.7943 nM
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CP0422489
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6-[2-(4-isoquinolin-1-ylpiperazin-1-yl)ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H24N4O2
|
1
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| 1 |
Ki = 0.7943 nM
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CP0126586
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1-methyl-6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]oxazine
Show/Hide
|
C26H28N6O
|
1
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| 1 |
Ki = 0.7943 nM
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CP0386020
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1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C26H28N4O
|
1
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| 1 |
Ki = 0.7943 nM
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CP0406080
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1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C26H30N4O
|
1
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| 1 |
Ki = 0.7943 nM
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CP0454396
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5-[2-[(2R)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
|
C27H29FN4O
|
1
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| 1 |
Ki = 0.7943 nM
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CP0040401
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N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]methanesulfonamide
Show/Hide
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C23H28N4O2S
|
1
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| 1 |
Ki = 0.7943 nM
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CP0442449
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6-methoxy-8-(4-methyl-[1,4]diazepan-1-yl)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (4-morpholin-4--phenyl)amide
Show/Hide
|
C27H33N5O4
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1
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| 1 |
Ki = 0.9 nM
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CP0422490
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8-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
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| 1 |
Ki = 1 nM
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CP0036547
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine
Show/Hide
|
C26H27N5O
|
1
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| 1 |
Ki = 1 nM
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CP0089790
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(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C31H34N6O2
|
1
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| 1 |
Ki = 1 nM
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CP0096951
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(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(morpholino)methanone
Show/Hide
|
C31H34N6O3
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1
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| 1 |
Ki = 1 nM
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CP0096953
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1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)ethanone
Show/Hide
|
C28H29N5O2
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1
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| 1 |
Ki = 1 nM
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CP0233604
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-2-(trifluoromethyl)-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C27H26F3N5O
|
1
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| 1 |
Ki = 1 nM
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CP0283739
|
8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H26N4O2
|
1
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| 1 |
Ki = 1 nM
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CP0845556
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N-(2-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
|
C29H30FN5O
|
1
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| 1 |
Ki = 1 nM
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CP0099712
|
3-(2-aminoethyl)-1H-indole-5-carboxamide
Show/Hide
|
C11H13N3O
|
1
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| 1 |
Ki = 1.259 nM
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CP0377438
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6-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
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| 1 |
Ki = 1.259 nM
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CP0096954
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N-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C28H30N6O2
|
1
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| 1 |
Ki = 1.259 nM
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CP0124306
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ethyl 6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxylate
Show/Hide
|
C29H31N5O3
|
1
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| 1 |
Ki = 1.259 nM
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CP0081200
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1-ethyl-3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]urea
Show/Hide
|
C25H31N5O
|
1
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| 1 |
Ki = 1.259 nM
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CP0648465
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N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-pyrazine Carboxamide
Show/Hide
|
C27H28N6O
|
1
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| 1 |
Ki = 1.259 nM
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CP0864963
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N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-propanamide
Show/Hide
|
C25H30N4O
|
1
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| 1 |
Ki = 1.259 nM
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CP0866064
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Ethyl(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate
Show/Hide
|
C25H30N4O2
|
1
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| 1 |
Ki = 1.259 nM
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CP0177439
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4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C27H31FN4O3
|
1
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| 1 |
Ki = 1.585 nM
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CP0177522
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5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C26H29FN4O3
|
1
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| 1 |
Ki = 1.585 nM
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CP0465757
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7-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
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| 1 |
Ki = 1.585 nM
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CP0064904
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,2-d][1,4]oxazine
Show/Hide
|
C26H27N5O
|
1
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| 1 |
Ki = 1.585 nM
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CP0068076
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(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(piperidin-1-yl)methanone
Show/Hide
|
C32H36N6O2
|
1
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| 1 |
Ki = 1.585 nM
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CP0069977
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2-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C27H29N5O
|
1
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| 1 |
Ki = 1.585 nM
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CP0216068
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N-(cyclopropylmethyl)-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C31H34N6O2
|
1
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| 1 |
Ki = 1.585 nM
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CP0226445
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azetidin-1-yl-[6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazin-3-yl]methanone
Show/Hide
|
C30H32N6O2
|
1
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| 1 |
Ki = 1.585 nM
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CP0233605
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine-3-carbonitrile
Show/Hide
|
C27H26N6O
|
1
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| 1 |
Ki = 1.585 nM
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CP0270386
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4-methyl-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
2
|
| 1 |
Ki = 1.585 nM
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| 2 |
Ki = 3.981 nM
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CP0688933
|
2-Methyl-5-(4-{2-[3-(1H-pyrazol-1-yl)phenyl]ethyl}-1-piperazinyl)quinoline
Show/Hide
|
C25H27N5
|
1
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| 1 |
Ki = 1.585 nM
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CP0845520
|
2-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)propanamide
Show/Hide
|
C26H32N4O
|
1
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| 1 |
Ki = 1.585 nM
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CP0845559
|
3-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide
Show/Hide
|
C30H32N4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
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CP0403061
|
6-[2-[3-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 1.995 nM
|
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CP0173138
|
N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]methanesulfonamide
Show/Hide
|
C25H31N3O3S
|
1
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| 1 |
Ki = 1.995 nM
|
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CP0377822
|
2-methyl-5-[2-[4-[(3-piperidin-1-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H37N3O
|
1
|
| 1 |
Ki = 1.995 nM
|
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CP0453856
|
2-methyl-5-[2-[4-[[3-[(3R)-3-methylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
Ki = 1.995 nM
|
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CP0036194
|
1,2-dimethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C28H31N5O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
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CP0332161
|
N-cyclopentyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C32H36N6O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
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CP0502083
|
5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
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C25H26N4O
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1
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| 1 |
Ki = 1.995 nM
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CP0040402
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3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-oxazolidin-2-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 1.995 nM
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CP0845523
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4-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)-1,3-thiazole-5-carboxamide
Show/Hide
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C27H29N5OS
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1
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| 1 |
Ki = 1.995 nM
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CP0845526
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2,2-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)propanamide
Show/Hide
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C27H34N4O
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1
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| 1 |
Ki = 1.995 nM
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CP0845528
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N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-N'-propylurea
Show/Hide
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C26H33N5O
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1
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| 1 |
Ki = 1.995 nM
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CP0855718
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N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1-propanesulfonamide
Show/Hide
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C25H32N4O2S
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1
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| 1 |
Ki = 1.995 nM
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CP0371946
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5-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H28FN3O3
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1
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| 1 |
Ki = 2.512 nM
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CP0403060
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6-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H25FN4O2
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1
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| 1 |
Ki = 2.512 nM
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CP0068072
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3-methyl-6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b][1,2,3]triazolo[1,5-d][1,4]oxazine
Show/Hide
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C26H28N6O
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1
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| 1 |
Ki = 2.512 nM
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CP0089820
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1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)ethanone O-methyl oxime
Show/Hide
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C29H32N6O2
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1
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| 1 |
Ki = 2.512 nM
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CP0097108
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-N-propan-2-yl-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C30H34N6O2
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1
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| 1 |
Ki = 2.512 nM
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CP0040398
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N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]benzamide
Show/Hide
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C29H30N4O
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1
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| 1 |
Ki = 2.512 nM
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CP0170130
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(6aR,9R)-N-[(2R,5S,8S,8aS)-8-benzyl-8a-hydroxy-2-methyl-5-(2-methylpropyl)-3,6-dioxo-7,8-dihydro-5H-[1,3]oxazolo[3,2-a]pyrazin-2-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Show/Hide
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C34H39N5O5
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1
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| 1 |
Ki = 3.162 nM
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CP0040404
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1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone
Show/Hide
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C25H29N5O
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1
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| 1 |
Ki = 3.162 nM
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CP0040416
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2-methyl-N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-thiazole-4-carboxamide
Show/Hide
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C27H29N5OS
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1
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| 1 |
Ki = 3.162 nM
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CP0116805
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1-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-3-phenylurea
Show/Hide
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C29H31N5O
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1
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| 1 |
Ki = 3.162 nM
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CP0845521
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2-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide
Show/Hide
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C29H29FN4O
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1
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| 1 |
Ki = 3.162 nM
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CP0855716
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3-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide
Show/Hide
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C29H29FN4O
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1
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| 1 |
Ki = 3.162 nM
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CP0861905
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N-(4-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
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C29H30FN5O
|
1
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| 1 |
Ki = 3.162 nM
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CP0496836
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6-methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (4-morpholin-4-ylphenyl)amide
Show/Hide
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C26H31N5O4
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1
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| 1 |
Ki = 3.5 nM
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CP0873316
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4-ethyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
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C28H33N3O3
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1
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| 1 |
Ki = 3.981 nM
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CP0461527
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5-[2-[4-[[3-[(3S,5R)-3,5-dimethylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
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C30H40N4O
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1
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| 1 |
Ki = 3.981 nM
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CP0845557
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2-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide
Show/Hide
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C30H32N4O2
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1
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| 1 |
Ki = 3.981 nM
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CP0855722
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N-(1,1-Dimethylethyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
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C27H35N5O
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1
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| 1 |
Ki = 3.981 nM
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CP0861892
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N-(3-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
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C29H30FN5O
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1
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| 1 |
Ki = 3.981 nM
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CP0900503
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4-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide
Show/Hide
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C30H32N4O2
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1
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| 1 |
Ki = 3.981 nM
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CP0860616
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3-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
Show/Hide
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C20H22ClN3O2S
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1
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| 1 |
Ki = 4.3 nM
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CP0374349
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2-methyl-5-[2-[4-[[3-(1-methylpiperidin-4-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
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C30H39N3O
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1
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| 1 |
Ki = 5.012 nM
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CP0845530
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4-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide
Show/Hide
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C29H29FN4O
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1
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| 1 |
Ki = 5.012 nM
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CP0729034
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4-methyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
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C27H31N3O3
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1
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| 1 |
Ki = 6.31 nM
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CP0433937
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6-[4-[4-(2-methylquinolin-5-yl)piperazin-1-yl]butyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H30N4O2
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1
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| 1 |
Ki = 6.31 nM
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CP0214664
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2-(dimethylamino)-N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]acetamide
Show/Hide
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C28H36N4O2
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1
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| 1 |
Ki = 6.31 nM
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CP0388729
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2-methyl-5-[2-[4-[(3-piperidin-4-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
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C29H37N3O
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1
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| 1 |
Ki = 6.31 nM
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CP0461521
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2-methyl-5-[2-[4-[[3-(4-methylpiperazin-1-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
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C29H38N4O
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1
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| 1 |
Ki = 6.31 nM
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CP0379189
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2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethylamine
Show/Hide
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C16H16N2O2S
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1
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| 1 |
Ki = 6.5 nM
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CP0146095
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4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
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C26H30N4O3
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1
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| 1 |
Ki = 7.943 nM
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CP0398939
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6-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 7.943 nM
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CP0382051
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2-methyl-5-[2-[4-[[3-(4-methyl-1,4-diazepan-1-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
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C30H40N4O
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1
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| 1 |
Ki = 7.943 nM
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CP0450459
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2-methyl-5-[2-[4-[(3-pyridin-4-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
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C29H31N3O
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1
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| 1 |
Ki = 7.943 nM
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CP0041018
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]tetrazolo[1,5-d][1,4]oxazine
Show/Hide
|
C24H25N7O
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1
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| 1 |
Ki = 7.943 nM
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CP0861908
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3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline
Show/Hide
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C22H26N4
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1
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| 1 |
Ki = 7.943 nM
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CP0777252
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2-Iodo-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
Show/Hide
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C20H22IN3O2S
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1
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| 1 |
Ki = 9.3 nM
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CP0496833
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6-fluoro-8-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (4-morpholin-4-ylphenyl)amide
Show/Hide
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C25H28FN5O3
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1
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| 1 |
Ki = 9.3 nM
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CP0152118
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6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H29N3O3
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1
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| 1 |
Ki = 10 nM
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CP0378377
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8-{[3-(2-Methoxy-phenyl)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C26H32N2O2
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1
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| 1 |
Ki = 11 nM
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CP0378553
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8-[(3-Phenyl-propyl)-propyl-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C25H30N2O
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1
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| 1 |
Ki = 11 nM
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CP0330654
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2-[1-(benzenesulfonyl)indol-4-yl]-N,N-dimethylethanamine
Show/Hide
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C18H20N2O2S
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1
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| 1 |
Ki = 11 nM
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CP0461524
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2-methyl-5-[2-[4-[(3-pyridin-3-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
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C29H31N3O
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1
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| 1 |
Ki = 12.59 nM
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CP0845529
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N-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Acetamide
Show/Hide
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C25H30N4O
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1
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| 1 |
Ki = 12.59 nM
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CP0374866
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(8R)-8-[3-phenylpropyl(propyl)amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C25H30N2O
|
1
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| 1 |
Ki = 14 nM
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CP0873359
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2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
Show/Hide
|
C20H22ClN3O2S
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1
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| 1 |
Ki = 15 nM
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CP0377813
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2-methyl-5-[2-[4-[[3-[(3S)-3-methylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H38N4O
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1
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| 1 |
Ki = 15.85 nM
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CP0372019
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7-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28FN3O3
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1
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| 1 |
Ki = 19.95 nM
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CP0509509
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(8R)-8-(dimethylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C15H18N2O
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1
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| 1 |
Ki = 20 nM
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CP0146096
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4-ethyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C27H32N4O3
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1
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| 1 |
Ki = 25.12 nM
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CP0216724
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6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-4-phenethyl-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C33H36N4O3
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1
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| 1 |
Ki = 25.12 nM
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CP0465888
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6-[2-[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H27N3O3
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1
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| 1 |
Ki = 25.12 nM
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CP0442444
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6-fluoro-4-methoxy-8-(4-methyl-piperazin-1-yl)-quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amide
Show/Hide
|
C26H30FN5O3
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1
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| 1 |
Ki = 30 nM
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CP0513848
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6-[[1-[2-(6-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H28FN3O3
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1
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| 1 |
Ki = 31.62 nM
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CP0091710
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4-butyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C29H36N4O3
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1
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| 1 |
Ki = 31.62 nM
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CP0344597
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6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-4-propyl-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
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C28H34N4O3
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1
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| 1 |
Ki = 31.62 nM
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CP0880810
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4-isobutyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
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C29H36N4O3
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1
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| 1 |
Ki = 31.62 nM
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CP0398938
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6-[2-(4-quinolin-8-ylpiperazin-1-yl)ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H24N4O2
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1
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| 1 |
Ki = 31.62 nM
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CP0417819
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5-[2-[4-[[3-[(2S,5R)-2,5-dimethylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C30H40N4O
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1
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| 1 |
Ki = 31.62 nM
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CP0502082
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6-fluoro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C26H27FN4O
|
1
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| 1 |
Ki = 31.62 nM
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CP0845558
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3-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-tetrahydro-2H-1,3-oxazin-2-one
Show/Hide
|
C26H30N4O2
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1
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| 1 |
Ki = 31.62 nM
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CP0458808
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8-((3R)-(+)-3-dimethylamino-pyrrolidin-1-yl)-6-methoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid(4-morpholin-4-yl-phenyl)amide
Show/Hide
|
C27H33N5O4
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1
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| 1 |
Ki = 35 nM
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CP0858844
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4-isopropyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C29H35N3O3
|
1
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| 1 |
Ki = 39.81 nM
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CP0382052
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5-[2-[4-[[3-(furan-3-yl)phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C28H30N2O2
|
1
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| 1 |
Ki = 39.81 nM
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CP0388728
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2-methyl-5-[2-[4-[(3-pyrrolidin-1-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C28H35N3O
|
1
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| 1 |
Ki = 39.81 nM
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CP0845522
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1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-tetrahydro-2(1H)-pyrimidinone
Show/Hide
|
C26H31N5O
|
1
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| 1 |
Ki = 39.81 nM
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CP0845527
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1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,5-pyrrolidinedione
Show/Hide
|
C26H28N4O2
|
1
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| 1 |
Ki = 39.81 nM
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CP0392682
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N-[3-(2-methoxyphenyl)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C25H32N2O
|
1
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| 1 |
Ki = 40 nM
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CP0424195
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8-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C22H26N2OS
|
1
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| 1 |
Ki = 46 nM
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CP0425117
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8-(Allyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C19H24N2O
|
1
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| 1 |
Ki = 49 nM
|
|
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CP0423703
|
6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]azetidin-3-yl]methoxy]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25N3O4
|
1
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| 1 |
Ki = 50.12 nM
|
|
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CP0433939
|
6-[3-[4-(2-methylquinolin-5-yl)piperazin-1-yl]propyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0434233
|
4-dimethylamino-6-methoxy-8-(4-methyl-piperazin-1-yl)-quinoline-2-carboxylic acid (4-morpholin-4-ylphenyl)amide
Show/Hide
|
C28H36N6O3
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0392154
|
8-(Phenethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C24H28N2O
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0439878
|
5-[2-[4-(1H-benzimidazol-4-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0201704
|
4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C32H34N4O3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0377812
|
4-methyl-1-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperazin-2-one
Show/Hide
|
C29H36N4O2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0388730
|
2-methyl-5-[2-[4-[(3-phenylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C30H32N2O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0496867
|
2-methyl-5-[2-[4-[(4-methyl-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]quinoline
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0382035
|
2-methyl-5-[2-[4-[[3-(1-methylsulfonylpiperidin-4-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C30H39N3O3S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0853639
|
2-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
Show/Hide
|
C19H20ClN3O2S
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0446420
|
2-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]-7H-1,2-benzoxazin-6-one
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0897868
|
6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0380845
|
8-(Methyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0376302
|
8-{[4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-butyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki = 115 nM
|
|
|
|
CP0380900
|
(8R)-8-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl-propylamino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0377437
|
6-[2-[4-(8-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0374348
|
1-methyl-4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperazin-2-one
Show/Hide
|
C29H36N4O2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0377823
|
4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]morpholine
Show/Hide
|
C28H35N3O2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0056626
|
(8R)-N,N-dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C18H26N2
|
1
|
| 1 |
Ki = 139 nM
|
|
|
|
CP0461737
|
6-[[1-[2-(8-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28ClN3O3
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0439874
|
5-[2-[4-(1H-indol-5-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0388749
|
(2S,6R)-2,6-dimethyl-4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]morpholine
Show/Hide
|
C30H39N3O2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0388750
|
1-[4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperidin-1-yl]ethanone
Show/Hide
|
C31H39N3O2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0442445
|
8-[ethyl-(1-ethyl-pyrrolidin-3-yl)-amino]-6-methoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amide
Show/Hide
|
C29H37N5O4
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0448144
|
8-{[3-(3-Chloro-phenoxy)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C25H29ClN2O2
|
1
|
| 1 |
Ki = 187 nM
|
|
|
|
CP0418991
|
[1-(benzenesulfonyl)-4-[2-(dimethylamino)ethyl]indol-2-yl]-phenylmethanone
Show/Hide
|
C25H24N2O3S
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0428818
|
8-(Cyclopropylmethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C20H26N2O
|
1
|
| 1 |
Ki = 196 nM
|
|
|
|
CP0079263
|
2-methyl-5-[2-[4-(quinolin-8-ylmethyl)piperazin-1-yl]ethoxy]quinoline
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0404669
|
5-[2-[4-[(4-chloro-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C23H25ClN4O3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0465889
|
6-[[1-[2-(2-methylquinolin-5-yl)oxypropyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C27H31N3O3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0378469
|
(8R)-N-(2-methylpropyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C19H28N2
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0378588
|
4,4-Dimethyl-1-{4-[propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amino]-butyl}-piperidine-2,6-dione
Show/Hide
|
C26H37N3O2
|
1
|
| 1 |
Ki = 224 nM
|
|
|
|
CP0448143
|
8-Propylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C16H20N2O
|
1
|
| 1 |
Ki = 227 nM
|
|
|
|
CP0064163
|
(8R)-N,N-dimethyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 228 nM
|
|
|
|
CP0432290
|
(3-Phenyl-propyl)-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-ylmethyl)-amine
Show/Hide
|
C22H26N2
|
1
|
| 1 |
Ki = 228 nM
|
|
|
|
CP0419374
|
N-[3-(3-chlorophenoxy)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C24H29ClN2O
|
1
|
| 1 |
Ki = 243 nM
|
|
|
|
CP0467378
|
N-(2-phenylethyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C23H28N2
|
1
|
| 1 |
Ki = 249 nM
|
|
|
|
CP0399848
|
2-amino-4-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]phenol
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0404695
|
5-[2-[4-[(4-fluoro-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C23H25FN4O3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0436208
|
2-methyl-5-[2-[4-(quinolin-5-ylmethyl)piperazin-1-yl]ethoxy]quinoline
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0271827
|
(+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0442447
|
8-[(3-dimethylamino-propyl)-methyl-amino]-6-methoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid(4-morpholin-4-yl-phenyl)amide
Show/Hide
|
C27H35N5O4
|
1
|
| 1 |
Ki = 292 nM
|
|
|
|
CP0339112
|
4-phenyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
Show/Hide
|
C25H24N4O2S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0371948
|
8-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0436211
|
5-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]quinazoline
Show/Hide
|
C25H27N5O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0495389
|
5-[2-[4-[(4-methoxy-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C24H28N4O4
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0433940
|
6-[[1-[3-(2-methylquinolin-5-yl)oxypropyl]azetidin-3-yl]methoxy]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H27N3O4
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0861232
|
3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide with di TFA
Show/Hide
|
C38H47F6N3O5
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0312260
|
2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8-diol
Show/Hide
|
C16H26N2O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0406075
|
5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0258010
|
(+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
Show/Hide
|
C18H26N2
|
1
|
| 1 |
Ki = 349 nM
|
|
|
|
CP0496834
|
8-[(2-dimethylamino-ethyl)-methyl-amino]-6-methoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid(4-morpholin-4-yl-phenyl)amide
Show/Hide
|
C26H33N5O4
|
1
|
| 1 |
Ki = 392 nM
|
|
|
|
CP0185590
|
4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide
Show/Hide
|
C18H22BrN3O3S
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0035199
|
5-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0403124
|
5-[2-[4-(1H-indol-7-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0446421
|
4-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]-2-nitrophenol
Show/Hide
|
C23H26N4O4
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0433941
|
6-[1-[3-(2-methylquinolin-5-yl)oxypropyl]azetidin-3-yl]oxy-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25N3O4
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0446892
|
1-methyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0409092
|
[3-[2-(dimethylamino)ethyl]-5-hydroxyindol-1-yl]-phenylmethanone
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
Ki = 420 nM
|
|
|
|
CP0382288
|
N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C15H20N2
|
1
|
| 1 |
Ki = 483 nM
|
|
|
|
CP0208303
|
5-chloro-2-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-3-sulfonamide
Show/Hide
|
C22H21ClN4O2S2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0306083
|
5-chloro-3-methyl-N-[4-(4-methylpiperazin-1-yl)quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0388359
|
N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]-4-phenylbenzamide
Show/Hide
|
C28H26ClN5O2
|
1
|
| 1 |
Ki = 524.81 nM
|
|
|
|
CP0388360
|
N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C29H28ClN5O2
|
1
|
| 1 |
Ki = 588.84 nM
|
|
|
|
CP0111551
|
5-chloro-N-(4-piperazin-1-ylquinolin-6-yl)naphthalene-2-sulfonamide
Show/Hide
|
C23H21ClN4O2S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0165719
|
N-[3-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H26ClN3O3S2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0183577
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid ((S)-3-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl-4-methoxy-phenyl)-amide
Show/Hide
|
C23H26ClN3O3S2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0332841
|
6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-8-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27ClFN3O3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0404673
|
5-[2-[4-[(2,5-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C23H25Cl2N3O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0433938
|
6-[2-[4-[(2-methylquinolin-5-yl)oxymethyl]piperidin-1-yl]acetyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27N3O4
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0847634
|
(E)-N-[4'-(Phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-N-pyridin-3-ylmethyl-acrylamide TFA
Show/Hide
|
C39H36F3N3O3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0853819
|
(E)-N-(2-Dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-acrylamide TFA
Show/Hide
|
C37H40F3N3O3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0399906
|
N-[5-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C29H28ClN5O2
|
1
|
| 1 |
Ki = 776.25 nM
|
|
|
|
CP0113176
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Show/Hide
|
C21H24ClN3O3S2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0674190
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid (4-methoxy-3-piperazin-1-yl-phenyl)-amide hydrochloride
Show/Hide
|
C20H23Cl2N3O3S2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0041243
|
5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride
Show/Hide
|
C20H22ClN3O3S2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0378357
|
6-[[1-[2-(8-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0318039
|
3-(2-Dimethylamino-ethyl)-1H-indole-2-carboxylic acid ethyl ester
Show/Hide
|
C15H20N2O2
|
1
|
| 1 |
Ki = 910 nM
|
|
|
|
CP0401280
|
8-(Benzyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C23H26N2O
|
1
|
| 1 |
Ki = 992 nM
|
|
|
|
CP0051242
|
(R)-1-(2-(1-(3-bromo-benzenesulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
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C18H27BrN2O2S
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1
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| 1 |
Ki = 1000 nM
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CP0096286
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(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol
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C18H28N2O3S
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1
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| 1 |
Ki = 1000 nM
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CP0296883
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7-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
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C26H27F2N3O3
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1
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| 1 |
Ki = 1000 nM
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CP0464205
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2-methyl-5-[2-[4-[(3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperidin-1-yl]ethoxy]quinoline-7-carbonitrile
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C27H28N4O3
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1
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| 1 |
Ki = 1000 nM
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CP0082421
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5-chloro-3-methyl-N-(2-methyl-4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
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C23H23ClN4O2S2
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1
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| 1 |
Ki = 1258.93 nM
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CP0495740
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
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C26H28ClN3O3
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1
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| 1 |
Ki = 1258.93 nM
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CP0461824
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6-methoxy-4-methylamino-8-(4-methyl-piperazin-1-yl)-quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amide
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C27H34N6O3
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1
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| 1 |
Ki = 1300 nM
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CP0271460
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(R)-1-(2-(1-(3,4-Dichloro-benzene sulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
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C18H26Cl2N2O2S
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1
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| 1 |
Ki = 1584.89 nM
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CP0182705
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(R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt)
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C19H30N2O2S
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1
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| 1 |
Ki = 1584.89 nM
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CP0081712
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4-tert-butyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
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C23H28N4O2S
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1
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| 1 |
Ki = 1584.89 nM
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CP0295528
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-5-fluoro-4H-1,4-benzoxazin-3-one
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C26H27ClFN3O3
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1
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| 1 |
Ki = 1584.89 nM
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CP0437569
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(8S)-8-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl-propylamino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde;hydrate
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C27H37N3O3
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1
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| 1 |
Ki = 1617 nM
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CP0044323
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(8S)-N,N-dimethyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C14H18N2
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1
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| 1 |
Ki = 1690 nM
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CP0173778
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5-chloro-3-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
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C22H21ClN4O2S2
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1
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| 1 |
Ki = 1995.26 nM
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CP0332842
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-7-fluoro-4H-1,4-benzoxazin-3-one
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C26H27ClFN3O3
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1
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| 1 |
Ki = 1995.26 nM
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CP0404672
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5-[2-[4-[(3,4-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
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C23H25Cl2N3O
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1
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| 1 |
Ki = 1995.26 nM
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CP0045069
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2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N,N-dimethylethanamine
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C19H22N2O3S
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1
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| 1 |
Ki = 2200 nM
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CP0216619
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(8S)-N,N-dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C18H26N2
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1
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| 1 |
Ki = 2275 nM
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CP0255950
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2-[1-(benzenesulfonyl)indol-3-yl]-N,N-dimethylethanamine
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C18H20N2O2S
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1
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| 1 |
Ki = 2300 nM
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CP0343547
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5-chloro-3-methyl-N-[4-[(3S)-3-methylpiperazin-1-yl]quinolin-6-yl]-1-benzothiophene-2-sulfonamide
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C23H23ClN4O2S2
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1
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| 1 |
Ki = 2511.89 nM
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CP0186950
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(4S,5S)-4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-5-ol
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C20H22N2O3S
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1
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| 1 |
Ki = 3100 nM
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CP0170807
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5-chloro-3-ethyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClN4O2S2
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1
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| 1 |
Ki = 3162.28 nM
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CP0198069
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(R)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine(10)
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C22H30N2O2S
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1
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| 1 |
Ki = 3981.07 nM
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CP0216543
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N-[3-(1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl)-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
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C24H28ClN3O3S2
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1
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| 1 |
Ki = 3981.07 nM
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CP0428133
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Benzyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
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C22H26N2
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1
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| 1 |
Ki = 4605 nM
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CP0475223
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1-[4-(benzenesulfonyl)-4-methylpentyl]-3-phenylpiperidine
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C23H31NO2S
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1
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| 1 |
Ki = 7700 nM
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CP0433935
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6-[[4-[(2-methylquinolin-5-yl)oxymethyl]piperidin-1-yl]methyl]-4H-1,4-benzoxazin-3-one
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C25H27N3O3
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1
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| 1 |
Ki > 10000 nM
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CP0441452
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6-[[4-(2-methylquinolin-5-yl)piperazin-1-yl]methyl]-4H-1,4-benzoxazin-3-one
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C23H24N4O2
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1
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| 1 |
Ki > 10000 nM
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CP0507914
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6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H28FN3O3
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1
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| 1 |
Ki < 1000 nM
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CP0442446
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8-((3S)-3-dimethylamino-pyrrolidin-1-yl)-6-methoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid(4-morpholin-4-yl-phenyl)amide
Show/Hide
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C27H33N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0532203
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6-methoxy-8-[methyl-(1-methyl-pyrrolidin-3-yl)-amino]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amide
Show/Hide
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C27H33N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0406074
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1,6-dimethyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
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C28H32N4O
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1
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| 1 |
Ki > 1000 nM
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CP0406076
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1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperidin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C28H31N3O
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1
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| 1 |
Ki > 1000 nM
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CP0437527
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5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
Show/Hide
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C28H31FN4O
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1
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| 1 |
Ki > 1000 nM
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CP0502072
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5-[2-[2,2-dimethyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
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C28H32N4O
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1
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| 1 |
Ki > 1000 nM
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CP0502075
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1,6-dimethyl-5-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C28H32N4O
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1
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| 1 |
Ki > 1000 nM
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CP0505428
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5-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
Show/Hide
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C27H29FN4O
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1
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| 1 |
Ki > 1000 nM
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CP0526143
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6-[[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H25N3O3
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1
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| 1 |
Ki > 2511.89 nM
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CP0712961
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(R)-sulfonamide1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
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C23H32N2O2S
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1
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| 1 |
Ki < 3162.28 nM
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CP0475225
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5-[1-[4-(benzenesulfonyl)-4-methylpentyl]piperidin-3-yl]-1,3-oxazole
Show/Hide
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C20H28N2O3S
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1
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| 1 |
Ki > 5000 nM
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CP0156235
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3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
Show/Hide
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C18H30N2O2S
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1
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| 1 |
Ki < 5011.87 nM
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CP0433950
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6-[2-[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]acetyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H25N3O4
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1
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| 1 |
Ki > 5011.87 nM
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CP0376451
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ethyl (3R)-1-[4-(benzenesulfonyl)-4-methylpentyl]piperidine-3-carboxylate
Show/Hide
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C20H31NO4S
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1
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| 1 |
Ki > 7000 nM
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CP0386567
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1-[4-(benzenesulfonyl)-4-methylpentyl]-3-(trifluoromethyl)piperidine
Show/Hide
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C18H26F3NO2S
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1
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| 1 |
Ki > 7000 nM
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CP0475224
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(4aS,8aR)-2-[4-(benzenesulfonyl)-4-methylpentyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline
Show/Hide
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C21H33NO2S
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1
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| 1 |
Ki > 7000 nM
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CP0658944
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(RS)-1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
Show/Hide
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C23H32N2O2S
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1
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| 1 |
Ki < 10000 nM
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CP0485418
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5-[2-[4-[(2,6-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
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C23H25Cl2N3O
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1
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| 1 |
Ki < 10000 nM
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