Brief Information of the Compound and Protein
Compound Name
1-NP
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PubChem ID
CID: 1342
SID: 15195770
Canonical SMILES
C1CN(CCN1)c1cccc2ccccc12
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Compound Formula C14H16N2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
Ki = 10.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 10.6 nM