General Information of the Compound
| Compound ID |
CP0061753
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| Compound Name |
1-NP
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| Synonyms |
1-NP
1-(1-Naphthyl)piperazine
1-(naphth-1-yl)piperazine
1-(naphthalen-1-yl)piperazine
1-Naphthalen-1-yl-piperazine
1-Naphthylpiperazine
1-naphthalen-1-ylpiperazine
1-naphthylpiperazine
4-(1-naphthyl) piperazine
4-(1-naphthyl)piperazine
4-(naphth-1-yl)piperazine
57536-86-4
AC1L1B9K
AC1Q1INU
Biomol-NT_000100
CHEMBL277120
GTPL3
Lopac-S-003
N-(1- naphthyl)piperazine
N-(1-naphthyl) piperazine
N-(1-naphthyl)-piperazine
N-(1-naphthyl)piperazine
Naphthylpiperazine
Oprea1_621306
Piperazine, 1-(1-naphthalenyl)-
Piperazine,1-(1-naphthalenyl)-
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| Structure |
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| Formula |
C14H16N2
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| Molecular Weight |
212.296
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| Canonical SMILES |
C1CN(CCN1)c1cccc2ccccc12
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| InChI |
InChI=1S/C14H16N2/c1-2-6-13-12(4-1)5-3-7-14(13)16-10-8-15-9-11-16/h1-7,15H,8-11H2
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| InChIKey |
VNICFCQJUVFULD-UHFFFAOYSA-N
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| CAS |
57536-86-4
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
Protein ID: PT01202, 5-hydroxytryptamine receptor 1B
Protein ID: PT00827, 5-hydroxytryptamine receptor 1D
Protein ID: PT01746, 5-hydroxytryptamine receptor 7
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Clinical Information about the Compound
Drug 1 ( 1-naphthylpiperazine )
| Drug Name | 1-naphthylpiperazine | ||
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| Target(s) |
5-HT 1D receptor (HTR1D)
Agonist
5-HT 6 receptor (HTR6)
Agonist
5-HT 1A receptor (HTR1A)
Agonist
5-HT 7 receptor (HTR7)
Agonist
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