Brief Information of the Compound and Protein
Compound Name
6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
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PubChem ID
CID: 9909089
SID: 14879267
Canonical SMILES
Cc1ccc2c(cccc2n1)N1CCN(CCc2ccc3OCC(=O)Nc3c2)CC1
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Compound Formula C24H26N4O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
Ki = 0.1995 nM
   TI
   LI
   LO
   TS
2
Ki = 0.5012 nM
   TI
   LI
   LO
   TS
3
Ki = 251.19 nM
   TI
   LI
   LO
   TS