Brief Information of the Compound and Protein
Compound Name
Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
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PubChem ID
CID: 10386282
SID: 15401765
Canonical SMILES
C(Cc1c[nH]c2ccc(cc12)-n1cnnc1)N1CC[C@@H](CNCc2ccccc2)C1
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Compound Formula C24H28N6
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
2
IC50 = 47 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 47 nM