Brief Information of the Compound and Protein
Compound Name
 Compound Info 
14C-5-hydroxy tryptamine creatinine disulfate
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 PubChem ID
CID: 5202
SID: 15120541
Canonical SMILES
NCCc1c[nH]c2ccc(O)cc12
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Compound Formula C10H12N2O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 4.67 nM
   TI
   LI
   LO
   TS
2
Ki = 5.012 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 4.82 nM
   TI
   LI
   LO
   TS
2
Ki = 1.1 nM
   TI
   LI
   LO
   TS
3
Ki = 6.76 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 4.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM
2 IC50 = 6.5 nM
3 IC50 = 12 nM
4 IC50 = 16 nM
5 IC50 = 29 nM
6 Ki = 4 nM
7 Ki = 6.76 nM
8 Ki = 7.1 nM
9 Ki = 14 nM
10 Ki = 18 nM