Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,4S)-3-fluoro-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
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 PubChem ID
CID: 71450983
Canonical SMILES
CN(Cc1ccccc1C(F)(F)F)[C@H]1CCN(CCCc2c[nH]c3ccc(cc23)-n2cnnc2)C[C@H]1F
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Compound Formula C27H30F4N6
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS