Brief Information of the Compound and Protein
Compound Name
3-[2-((R)-3-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
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PubChem ID
CID: 10739818
SID: 15776108
Canonical SMILES
C(Cc1c[nH]c2ccc(cc12)-n1cnnc1)N1CC[C@@H](COCc2ccccc2)C1
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Compound Formula C24H27N5O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
2
IC50 = 88 nM
   TI
   LI
   LO
   TS