| Compound ID |
Compound Name |
Compound Formula |
|
CP0046394
|
BMS-907351
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|
C28H24FN3O5
|
1
|
| 1 |
GI50 = 120 nM
|
|
|
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CP0065824
|
3-(5-cyclopropyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C14H16N6O
|
1
|
| 1 |
GI50 = 240 nM
|
|
|
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CP0156701
|
1-cyclohexyl-3-(5-cyclopropyl-1,2-oxazol-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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|
C17H20N6O
|
1
|
| 1 |
GI50 = 290 nM
|
|
|
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CP0230028
|
3-(5-cyclopropyl-1,2-oxazol-3-yl)-1-(oxan-4-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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|
C16H18N6O2
|
1
|
| 1 |
GI50 = 940 nM
|
|
|
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CP0062729
|
3-(2-phenylethynyl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C16H15N5
|
1
|
| 1 |
GI50 = 2540 nM
|
|
|
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CP0156708
|
3-(5-ethyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C13H16N6O
|
1
|
| 1 |
GI50 = 2610 nM
|
|
|
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CP0095871
|
3-(5-cyclopropyl-1,2-oxazol-3-yl)-1-methylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C12H12N6O
|
1
|
| 1 |
GI50 = 3510 nM
|
|
|
|
CP0364644
|
1-[4-amino-3-(5-cyclopropyl-1,2-oxazol-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-2-methylpropan-2-ol
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|
C15H18N6O2
|
1
|
| 1 |
GI50 = 4250 nM
|
|
|
|
CP0083897
|
1-propan-2-yl-3-(5-propan-2-yl-1,2-oxazol-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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|
C14H18N6O
|
1
|
| 1 |
GI50 = 5130 nM
|
|
|
|
CP0106777
|
3-(1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C11H12N6O
|
1
|
| 1 |
GI50 = 7920 nM
|
|
|
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CP0140879
|
1-propan-2-yl-3-(5-pyridin-2-yl-1,2-oxazol-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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|
C16H15N7O
|
1
|
| 1 |
GI50 = 9260 nM
|
|
|
|
CP0198308
|
3-[(E)-phenylmethoxyiminomethyl]-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C16H18N6O
|
1
|
| 1 |
GI50 = 9270 nM
|
|
|
|
CP0071780
|
3-(5-cyclohexyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C17H22N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
|
CP0089052
|
3-(5-cyclopropyl-1,2-oxazol-3-yl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine
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|
C11H10N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
|
CP0095875
|
1-benzyl-3-(5-cyclopropyl-1,2-oxazol-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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|
C18H16N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
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CP0174991
|
3-(5-benzyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C18H18N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
|
CP0174992
|
3-(5-tert-butyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C15H20N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
|
CP0174993
|
3-(5-cyclopropyl-1,2-oxazol-3-yl)-1-heptylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C18H24N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
|
CP0181070
|
3-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C17H15FN6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
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CP0198875
|
3-(5-cyclopentyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C16H20N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
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CP0304455
|
3-(5-phenyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C17H16N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
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CP0309740
|
3-(5-phenyl-4,5-dihydro-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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|
C17H18N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
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CP0401663
|
(NE)-N-[(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)methylidene]hydroxylamine
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|
C9H12N6O
|
1
|
| 1 |
GI50 > 10000 nM
|
|
|
|
CP0268012
|
2-(4-(4-Ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2-fluorophenyl)-N-(3-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-5-yl)acetamide
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|
C22H21F4N3O4
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
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CP0242633
|
N-[4-(2,2-dimethyl-3-methylsulfonylpropyl)-3-(trifluoromethyl)phenyl]-2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]acetamide
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|
C28H30F4N2O5S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
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CP0244732
|
N-[4-(2-amino-2-methylpropyl)-3-(trifluoromethyl)phenyl]-2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]acetamide
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|
C26H27F4N3O3
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
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CP0097084
|
2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]-N-[4-(2-hydroxy-2-methylpropyl)-3-(trifluoromethyl)phenyl]acetamide
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|
C26H26F4N2O4
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
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CP0189108
|
2-(4-(4-Ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2-fluorophenyl)-N-(4-(3-hydroxy-2,2-dimethylpropyl)-3-(trifluoromethyl)phenyl)acetamide
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|
C27H28F4N2O4
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
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CP0213933
|
2-(4-(4-Ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2-fluorophenyl)-N-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)acetamide
Show/Hide
|
C22H21F4N3O4
|
1
|
| 1 |
IC50 = 11.1 nM
|
|
|
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CP0242632
|
N-[4-[(dimethylamino)methyl]-3-(trifluoromethyl)phenyl]-2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]acetamide
Show/Hide
|
C25H25F4N3O3
|
1
|
| 1 |
IC50 = 20.7 nM
|
|
|
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CP0242634
|
2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]-N-[3-(5-methyl-1,3,4-oxadiazol-2-yl)-5-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C25H20F4N4O4
|
1
|
| 1 |
IC50 = 29.5 nM
|
|
|
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CP0189107
|
N-[4-(1-cyanoethyl)-3-(trifluoromethyl)phenyl]-2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]acetamide
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|
C25H21F4N3O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
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CP0329627
|
N-[3-[(dimethylamino)methyl]-2-fluoro-5-(trifluoromethyl)phenyl]-2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]acetamide
Show/Hide
|
C25H24F5N3O3
|
1
|
| 1 |
IC50 = 70.2 nM
|
|
|
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CP0124203
|
2-(4-(4-Ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2-fluorophenyl)-N-(3-(trifluoromethyl)phenyl)acetamide
Show/Hide
|
C22H18F4N2O3
|
1
|
| 1 |
IC50 = 111.1 nM
|
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