Brief Information of the Compound and Protein
Compound Name
(NE)-N-[(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)methylidene]hydroxylamine
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PubChem ID
CID: 137148836
Canonical SMILES
CC(C)n1nc(\C=N\O)c2c(N)ncnc12
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Compound Formula C9H12N6O
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CL000425 TT Homo sapiens (Human)  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3680 nM
2 IC50 = 4900 nM