Brief Information of the Compound and Protein
Compound Name
3-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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PubChem ID
CID: 126592018
Canonical SMILES
CC(C)n1nc(-c2cc(on2)-c2ccc(F)cc2)c2c(N)ncnc12
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Compound Formula C17H15FN6O
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CL000425 TT Homo sapiens (Human)  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 150 nM