Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[(dimethylamino)methyl]-2-fluoro-5-(trifluoromethyl)phenyl]-2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]acetamide
    Show/Hide
 PubChem ID
CID: 145964261
Canonical SMILES
CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(cc(CN(C)C)c2F)C(F)(F)F)c(F)c1
    Show/Hide
Compound Formula C25H24F5N3O3
Compound Structure
Protein Name
 Protein Info 
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000425 TT
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 70.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.8 nM