Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]-N-[4-(2-hydroxy-2-methylpropyl)-3-(trifluoromethyl)phenyl]acetamide
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 PubChem ID
CID: 145970990
Canonical SMILES
CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(CC(C)(C)O)c(c2)C(F)(F)F)c(F)c1
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Compound Formula C26H26F4N2O4
Compound Structure
Protein Name
 Protein Info 
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000425 TT
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.4 nM