General Information of the Compound
| Compound ID |
CP0095871
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| Compound Name |
3-(5-cyclopropyl-1,2-oxazol-3-yl)-1-methylpyrazolo[3,4-d]pyrimidin-4-amine
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| Structure |
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| Formula |
C12H12N6O
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| Molecular Weight |
256.269
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| Canonical SMILES |
Cn1nc(-c2cc(on2)C2CC2)c2c(N)ncnc12
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| InChI |
InChI=1S/C12H12N6O/c1-18-12-9(11(13)14-5-15-12)10(16-18)7-4-8(19-17-7)6-2-3-6/h4-6H,2-3H2,1H3,(H2,13,14,15)
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| InChIKey |
OXVYQVULGJDEAV-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00951, Proto-oncogene tyrosine-protein kinase receptor Ret
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000077 | Ba/F3 | Mus musculus (Mouse) | 1 |
| 1 |
GI50 > 10000 nM
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TI
LI
LO
TS
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