General Information of the Compound
| Compound ID |
CP0027482
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| Compound Name |
5,6,7-Trihydroxyflavone
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| Synonyms |
3WL
491-67-8
49QAH60606
4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-
5,6,7-Trihydroxyflavone
5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
5,6,7-trihydroxy-2-phenyl-chromen-4-one
5,6,7-trihydroxy-2-phenylchromen-4-one
5,7-Trihydroxyflavone
AC1NQYPP
BAICALEIN
BaiKalein
Baicalein, 14
Baicalein, 8
Baicalein, 98%
Baicalein,(S)
Baicelein
Biacalein
CHEBI:2979
CHEMBL8260
FXNFHKRTJBSTCS-UHFFFAOYSA-N
MFCD00017459
NSC 661431
NSC661431
Noroxylin
SMR000112462
SR-01000597499
Sho-saiko-to
Tocris-1761
UNII-49QAH60606
baicalein
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| Structure |
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| Formula |
C15H10O5
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| Molecular Weight |
270.24
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| Canonical SMILES |
Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1
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| InChI |
InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
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| InChIKey |
FXNFHKRTJBSTCS-UHFFFAOYSA-N
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| CAS |
491-67-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06362, Cyclic AMP-responsive element-binding protein 1
Protein ID: PT03308, G-protein coupled receptor 35
Protein ID: PT06109, Geminin
Protein ID: PT02311, UDP-glucuronosyltransferase 1A1
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000220 | KB | Homo sapiens (Human) | 2 |
| 1 |
IC50 = 62300 nM
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TI
LI
LO
TS
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| 2 |
IC50 = 87100 nM
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TI
LI
LO
TS
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Clinical Information about the Compound
Drug 1 ( BAICALEIN )
| Drug Name | BAICALEIN | ||
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| Indication | |||
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