General Information of the Protein
| Protein ID |
PT01147
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| Protein Name |
L-selectin
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| Secondarily Protein Name |
CD62 antigen-like family member L
Leukocyte adhesion molecule 1
Leukocyte surface antigen Leu-8
Leukocyte-endothelial cell adhesion molecule 1
Lymph node homing receptor
TQ1
gp90-MEL
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| Gene Name |
SELL
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| Secondarily Gene Name |
LNHR
LYAM1
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| Sequence |
MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKKGKKSKRSMNDPY
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Adhesion
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| Function |
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).
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| Uniprot ID |
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| Ensembl ID | |||||
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| Subcellular Location |
Cell membrane
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Clinical Information about the Protein