General Information of the Cell Line
Cell Line ID
CL000457
Cell Line Name
BT-20
Synonyms
BT 20
BT20
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0178
Tissue Information
Breast
Disease
Invasive breast carcinoma of no special type (NCIt: C4194)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01045, Phosphoinositide 3-kinase alpha
Compound ID Compound Name Compound Formula
CP0054465
4-amino-2,6-dimethyl-N-(1H-pyrazol-4-yl)quinazoline-8-carboxamide
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C14H14N6O
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0195835
4-amino-2,6-dimethyl-N-(1H-pyrazol-5-yl)quinazoline-8-carboxamide
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C14H14N6O
 1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0195833
4-amino-2,6-dimethyl-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)quinazoline-8-carboxamide
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C18H16N6O
 1
1
IC50 = 43 nM
   TI
   LI
   LO
   TS
CP0282725
4-amino-2,6-dimethyl-N-(6-methylpyridin-3-yl)quinazoline-8-carboxamide
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C17H17N5O
 1
1
IC50 = 88 nM
   TI
   LI
   LO
   TS
CP0054466
4-amino-2-methyl-N-(6-methylpyridin-3-yl)quinazoline-8-carboxamide
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C16H15N5O
 1
1
IC50 = 112 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Breast)
Cell Line Name Organism Disease
MX-1 Homo sapiens (Human) Breast carcinoma
HCC1954 Homo sapiens (Human) Breast ductal carcinoma
HDQ-P1 Homo sapiens (Human) Breast ductal carcinoma
SUM159PT Homo sapiens (Human) Breast pleomorphic carcinoma
HCC1806 Homo sapiens (Human) Breast squamous cell carcinoma, acantholytic variant
BT-474 Homo sapiens (Human) Invasive breast carcinoma of no special type
Hs 578T Homo sapiens (Human) Invasive breast carcinoma of no special type
BT-549 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-10A Homo sapiens (Human) -
184B5 Homo sapiens (Human) -
UFH-001 Homo sapiens (Human) -
184A1N4 Homo sapiens (Human) -