| Compound ID |
Compound Name |
Compound Formula |
|
CP0087751
|
CHEMBL2375968
Show/Hide
|
C21H24FN5O4
|
1
|
| 1 |
IC50 = 5.24 nM
|
|
|
|
CP0225357
|
2-amino-8-(4-hydroxycyclohexyl)-4-methyl-6-(6-methylpyridin-3-yl)pteridin-7-one
Show/Hide
|
C19H22N6O2
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0344512
|
2-amino-8-[4-(2-hydroxyethoxy)cyclohexyl]-4-methyl-6-(6-methylpyridin-3-yl)pteridin-7-one
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|
C21H26N6O3
|
1
|
| 1 |
IC50 = 5.74 nM
|
|
|
|
CP0085266
|
2-[4-[2-amino-6-(5-fluoro-6-methoxypyridin-3-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetamide
Show/Hide
|
C22H25FN6O4
|
1
|
| 1 |
IC50 = 5.82 nM
|
|
|
|
CP0175377
|
2-[4-[2-amino-6-(5-fluoro-6-methoxypyridin-3-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetamide
Show/Hide
|
C22H25FN6O4
|
1
|
| 1 |
IC50 = 8.22 nM
|
|
|
|
CP0484145
|
2-amino-8-[4-(hydroxymethoxy)cyclohexyl]-4-methyl-6-(1H-pyrazol-4-yl)pyrido[2,3-d]pyrimidin-7-one
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|
C18H22N6O3
|
1
|
| 1 |
IC50 = 11.2 nM
|
|
|
|
CP0100626
|
CHEMBL1234354
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|
C22H27N5O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0344513
|
2-amino-8-(4-hydroxycyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpteridin-7-one
Show/Hide
|
C19H22N6O3
|
1
|
| 1 |
IC50 = 14.3 nM
|
|
|
|
CP0087752
|
2-[4-[2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetamide
Show/Hide
|
C22H26N6O4
|
1
|
| 1 |
IC50 = 19.3 nM
|
|
|
|
CP0307480
|
2-amino-8-[4-(hydroxymethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C21H25N5O4
|
1
|
| 1 |
IC50 = 21.6 nM
|
|
|
|
CP0108669
|
CHEMBL2375365
Show/Hide
|
C20H24N6O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0093336
|
2-[4-[2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetamide
Show/Hide
|
C22H26N6O4
|
1
|
| 1 |
IC50 = 23.3 nM
|
|
|
|
CP0085269
|
CHEMBL2375965
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|
C24H25N5O3
|
1
|
| 1 |
IC50 = 23.8 nM
|
|
|
|
CP0301406
|
2-amino-4-methyl-6-(6-methylpyridin-3-yl)-8-(tetrahydro-2H-pyran-4-yl)pteridin-7(8H)-one
Show/Hide
|
C18H20N6O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0108457
|
CHEMBL2375967
Show/Hide
|
C18H22N6O3
|
1
|
| 1 |
IC50 = 25.9 nM
|
|
|
|
CP0108458
|
2-amino-8-[4-(hydroxymethoxy)cyclohexyl]-6-(2-methoxypyrimidin-5-yl)-4-methylpyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C20H24N6O4
|
1
|
| 1 |
IC50 = 29.4 nM
|
|
|
|
CP0064730
|
2-[4-[2-amino-6-(2-methoxypyrimidin-5-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetamide
Show/Hide
|
C21H25N7O4
|
1
|
| 1 |
IC50 = 51.9 nM
|
|
|
|
CP0252047
|
2-[4-(2-amino-4-methyl-7-oxo-6-quinolin-3-ylpyrido[2,3-d]pyrimidin-8-yl)cyclohexyl]oxyacetamide
Show/Hide
|
C25H26N6O3
|
1
|
| 1 |
IC50 = 56.8 nM
|
|
|
|
CP0233812
|
2-amino-4-methyl-6-(1H-pyrazol-3-yl)-8-(tetrahydro-2H-pyran-4-yl)pteridin-7(8H)-one
Show/Hide
|
C15H17N7O2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0108668
|
2-[4-[2-amino-6-(2-methoxypyrimidin-5-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetamide
Show/Hide
|
C21H25N7O4
|
1
|
| 1 |
IC50 = 82.9 nM
|
|
|
|
CP0113510
|
2-amino-8-[4-(hydroxymethoxy)cyclohexyl]-4-methyl-6-quinolin-3-ylpyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C24H25N5O3
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0086788
|
2-[4-(2-amino-4-methyl-7-oxo-6-quinolin-3-ylpyrido[2,3-d]pyrimidin-8-yl)cyclohexyl]oxyacetamide
Show/Hide
|
C25H26N6O3
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0085267
|
US8633204, 305
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|
C19H23N7O3
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0307481
|
US8633204, 312
Show/Hide
|
C19H23N7O3
|
1
|
| 1 |
IC50 = 256 nM
|
|
|
|
CP0155436
|
2-amino-8-[4-(hydroxymethoxy)cyclohexyl]-4-methyl-6-(1-methylpyrazol-4-yl)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C19H24N6O3
|
1
|
| 1 |
IC50 = 288 nM
|
|
|
|
CP0563123
|
2-amino-8-[4-(hydroxymethoxy)cyclohexyl]-4-methyl-6-(1-methylpyrazol-4-yl)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C19H24N6O3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0085265
|
2-[4-[2-amino-4-methyl-6-(1-methylpyrazol-4-yl)-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetamide
Show/Hide
|
C20H25N7O3
|
1
|
| 1 |
IC50 = 376 nM
|
|
|
|
CP0093337
|
CHEMBL2375960
Show/Hide
|
C20H25N7O3
|
1
|
| 1 |
IC50 = 988 nM
|
|
|
|
CP0108670
|
2-[4-[2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxyacetic acid
Show/Hide
|
C22H25N5O5
|
1
|
| 1 |
IC50 = 2070 nM
|
|
|
