General Information of the Cell Line
Cell Line ID
CL000364
Cell Line Name
Hs 578T
Synonyms
HS 578T
Hs-578T
HS-578T
Hs_578t
Hs-578-T
HS-578-T
Hs 578.T
HS578T
Hs578T
Hs578t
HS0578T
578T
HS578
Hs578
Homo sapiens No. 578, tumor cells
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0332
Tissue Information
Breast
Disease
Invasive breast carcinoma of no special type (NCIt: C4194)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01014, Cysteine protease CPP32
Compound ID Compound Name Compound Formula
CP0210512
CID6851947
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C23H28N4O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003433
(Arylindolyl)maleimide deriv. 27
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C21H16N4O2  1
1
LC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0006369
6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile
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C32H31N5O3  1
1
GI50 = 3970 nM
   TI
   LI
   LO
   TS
CP0007711
(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid
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C26H31F3N4O3  1
1
GI50 = 121 nM
   TI
   LI
   LO
   TS
CP0039399
8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydroxyphenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
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C22H19N5O4  1
1
GI50 = 562 nM
   TI
   LI
   LO
   TS
CP0069210
US8569511, 1
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C22H20F2N6O2  1
1
IC50 = 1460 nM
   TI
   LI
   LO
   TS
CP0112599
US8569511, 2
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C23H22F2N6O2  1
1
IC50 = 947 nM
   TI
   LI
   LO
   TS
CP0142470
US10266537, Compound 93
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C29H27F3N6O2  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CP0370065
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
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C17H12ClN3OS  1
1
LC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0465282
4-N-(4-methoxyphenyl)-4-N-methyl-9H-pyrimido[4,5-b]indole-2,4-diamine
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C18H17N5O  1
1
GI50 = 11.5 nM
   TI
   LI
   LO
   TS
CP0906523
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
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C23H25ClN4O  1
1
GI50 = 62.3 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Breast)
Cell Line Name Organism Disease
MX-1 Homo sapiens (Human) Breast carcinoma
HCC1954 Homo sapiens (Human) Breast ductal carcinoma
HDQ-P1 Homo sapiens (Human) Breast ductal carcinoma
SUM159PT Homo sapiens (Human) Breast pleomorphic carcinoma
HCC1806 Homo sapiens (Human) Breast squamous cell carcinoma, acantholytic variant
BT-474 Homo sapiens (Human) Invasive breast carcinoma of no special type
BT-20 Homo sapiens (Human) Invasive breast carcinoma of no special type
BT-549 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-10A Homo sapiens (Human) -
184B5 Homo sapiens (Human) -
UFH-001 Homo sapiens (Human) -
184A1N4 Homo sapiens (Human) -