General Information of the Cell Line
Cell Line ID
CL000286
Cell Line Name
HCC1806
Synonyms
Hcc1806
HCC-1806
Hamon Cancer Center 1806
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1258
Tissue Information
Breast
Disease
Breast squamous cell carcinoma, acantholytic variant (NCIt: C40359)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03003, Histone-lysine N-methyltransferase EZH2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0025037
 Compound Info 
N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide
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C31H39N7O2
  1
1
IC50 = 79 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0025055
 Compound Info 
N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide
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C31H39N7O2
  1
1
IC50 = 174 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016806
 Compound Info 
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide
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C29H35N7O2
  1
1
IC50 = 324 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0024696
 Compound Info 
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide
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C29H35N7O2
  1
1
IC50 = 1995 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0021090
 Compound Info 
6-cyclopropyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-propan-2-ylindazole-4-carboxamide
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C22H26N4O2
  1
1
IC50 = 2510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0028621
 Compound Info 
6-cyclopropyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-propan-2-ylpyrazolo[3,4-b]pyridine-4-carboxamide
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C21H25N5O2
  1
1
IC50 = 10632 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Breast)
Cell Line Name Organism Disease
MX-1
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
HCC1954
 Cell Line Info 
Homo sapiens (Human) Breast ductal carcinoma
HDQ-P1
 Cell Line Info 
Homo sapiens (Human) Breast ductal carcinoma
SUM159PT
 Cell Line Info 
Homo sapiens (Human) Breast pleomorphic carcinoma
BT-474
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
Hs 578T
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
BT-20
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
BT-549
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-10A
 Cell Line Info 
Homo sapiens (Human) -
184B5
 Cell Line Info 
Homo sapiens (Human) -
UFH-001
 Cell Line Info 
Homo sapiens (Human) -
184A1N4
 Cell Line Info 
Homo sapiens (Human) -