Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide
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 PubChem ID
CID: 71268957
SID: 163493645
Canonical SMILES
CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccnc(c1)N1CCN(C)CC1
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Compound Formula C31H39N7O2
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000286 HCC1806
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 174 nM
   TI
   LI
   LO
   TS
CL000141 LNCaP
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.2 nM
2 Ki = 1.2 nM