7-(1-tert-butylpiperidin-4-yl)-5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)quinolin-2(1H)-one

7-(1-tert-butylpiperidin-4-yl)-5-(2-chloro-4-fluorophenyl)-1-(2,6-difluorophenyl)quinolin-2(1H)-one

7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-1,6-naphthyridin-2(1H)-one

7-(1-tert-butyl-1,2,3,6-tetrahydropyridin-4-yl)-5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)quinolin-2(1H)-one

7-(1-tert-butylpiperidin-4-yloxy)-1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)quinolin-2(1H)-one

5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl)quinolin-2(1H)-one

7-(8-aza-bicyclo[3.2.1]octan-3-yl)-5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)quinolin-2(1H)-one

5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(8-isopropyl-8-aza-bicyclo[3.2.1]octan-3-yl)quinolin-2(1H)-one

7-(1-tert-butylpiperidin-4-yl)-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)quinolin-2(1H)-one

methyl 2-[4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]piperidin-1-yl]propanoate

7-(1-tert-butylpiperidin-4-yl)-5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-1,6-naphthyridin-2(1H)-one

7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)quinolin-2(1H)-one

7-(1-tert-butylpiperidin-4-yloxy)-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)quinolin-2(1H)-one

7-(1-tert-butylpiperidin-4-yloxy)-5-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)quinolin-2(1H)-one

7-(1-tert-butylpiperidin-4-yloxy)-5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)quinolin-2(1H)-one

methyl 2-[4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]piperidin-1-yl]-2-methylpropanoate

(2S)-2-(4-(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2-dihydroquinolin-7-yl)piperidin-1-yl)propanoic acid

5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(2,2,6,6-tetramethyl-1,2,3,6-tetrahydropyridin-4-yl)quinolin-2(1H)-one

2-(4-(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2-dihydroquinolin-7-yl)piperidin-1-yl)-2-methylpropanoic acid

(2R)-2-(4-(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2-dihydroquinolin-7-yl)piperidin-1-yl)propanoic acid

1-(2,4-difluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]carbonyl}-1H-pyrazol-5-amine

1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]carbonyl}-1H-pyrazol-5-amine

[5-amino-1-(2,4-difluorophenyl)-1H-pyrazol-4-yl]-[3-(1-oxypyridin-3-yl)phenyl]methanone

1-(4-fluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]carbonyl}-1H-pyrazol-5-amine

1-(4-fluorophenyl)-4-({3-[3-(piperidin-1-yl)prop-1-yn-1-yl]phenyl}carbonyl)-1H-pyrazol-5-amine

3-(2-chlorophenyl)-1-[2-[[(2S)-3-hydroxy-3-methylbutan-2-yl]amino]pyrimidin-4-yl]-1-(4-methoxyphenyl)urea

4-benzoyl-1-(4-fluorophenyl)-1H-pyrazol-5-amine

3-(2-chlorophenyl)-1-(4-fluorophenyl)-1-[2-[[(2S)-3-hydroxy-3-methylbutan-2-yl]amino]pyrimidin-4-yl]urea

1-[2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)ethyl]cyclopentan-1-ol

1-(4-fluorophenyl)-4-({3-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}carbonyl)-1H-pyrazol-5-amine

1-[2-[[(2S)-3-hydroxy-3-methylbutan-2-yl]amino]pyrimidin-4-yl]-1-(4-methoxyphenyl)-3-(2-methylphenyl)urea

4-({3-[3-(dimethylamino)prop-1-yn-1-yl]phenyl}carbonyl)-1-(4-fluorophenyl)-1H-pyrazol-5-amine

1-(4-fluorophenyl)-4-{[4-(pyridin-3-yl)phenyl]carbonyl}-1H-pyrazol-5-amine

1-(4-fluorophenyl)-1-[2-[[(2S)-3-hydroxy-3-methylbutan-2-yl]amino]pyrimidin-4-yl]-3-(2-methylphenyl)urea

2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)ethan-1-ol

N-[4-methyl-3-[3-[4-(methylamino)-1,3,5-triazin-2-yl]pyridin-2-yl]oxyphenyl]-3-(1,1,2,2-tetrafluoroethoxy)benzamide

(2R)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenoxy)propane-1,2-diol

3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)prop-2-yn-1-ol

(2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenoxy)propane-1,2-diol

1-(4-fluorophenyl)-4-({3-[2-(4-methylpiperazin-1-yl)ethyl]phenyl}carbonyl)-1H-pyrazol-5-amine

1-(4-fluorophenyl)-4-({3-[2-(morpholin-4-yl)ethoxy]phenyl}carbonyl)-1H-pyrazol-5-amine

2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)ethane-1-sulfonamide

(5-Amino-1-O-tolyl-1H-pyrazol-4-yl)phenylmethanone

4-{[3-(2-aminoethyl)phenyl]carbonyl}-1-(4-fluorophenyl)-1H-pyrazol-5-amine

1-(4-fluorophenyl)-4-{[3-(2-methanesulfonylethyl)phenyl]carbonyl}-1H-pyrazol-5-amine

4-benzoyl-1-(2-methoxyphenyl)-1H-pyrazol-5-amine

3-(2-chlorophenyl)-1-(4-fluorophenyl)-1-[2-(oxan-4-ylamino)pyrimidin-4-yl]urea

4-benzoyl-1-(2-fluorophenyl)-1H-pyrazol-5-amine

(5-Amino-1-phenyl-1H-pyrazol-4-yl)phenylmethanone

4-benzoyl-1-(4-methoxyphenyl)-1H-pyrazol-5-amine

3-(2-chlorophenyl)-1-[2-[[(2S)-3-hydroxy-3-methylbutan-2-yl]amino]pyrimidin-4-yl]-1-phenylurea

1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]-3-(2-methylphenyl)-1-phenylurea

1-(4-fluorophenyl)-4-({3-[3-(morpholin-4-yl)propyl]phenyl}carbonyl)-1H-pyrazol-5-amine

1-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)ethane-1,2-diol

1-(4-fluorophenyl)-4-({3-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1H-pyrazol-5-amine

3-(2-chlorophenyl)-1-(4-fluorophenyl)-1-[2-[(1-propylsulfonylpiperidin-4-yl)amino]pyrimidin-4-yl]urea

4-benzoyl-1-(3-fluorophenyl)-1H-pyrazol-5-amine

3-[5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonyl]-benzonitrile

3-(2-fluorophenyl)-1-(4-fluorophenyl)-1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]urea

3-(2-chlorophenyl)-1-(4-fluorophenyl)-1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]urea

ethyl 4-[[4-[N-[(2-chlorophenyl)carbamoyl]-4-fluoroanilino]pyrimidin-2-yl]amino]piperidine-1-carboxylate

1-(4-fluorophenyl)-1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]-3-(2-methylphenyl)urea

3-(2-chlorophenyl)-1-(3-fluorophenyl)-1-[2-[[(1S)-1-phenylethyl]amino]pyrimidin-4-yl]urea

4-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)-2-methylbutan-2-ol

1-(4-fluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]carbonyl}-1H-pyrazol-5-amine

2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)propane-1,2,3-triol

1-(4-fluorophenyl)-4-({4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}carbonyl)-1H-pyrazol-5-amine

(5-amino-1-phenyl-1H-pyrazol-4-yl)phenylmethanone O-methyloxime

4-[5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonyl]benzonitrile

4-benzoyl-1-(3-nitrophenyl)-1H-pyrazol-5-amine

3-(2-chlorophenyl)-1-[4-(dimethylamino)phenyl]-1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]urea

3-(2-chlorophenyl)-1-(4-fluorophenyl)-1-(2-morpholin-4-ylpyrimidin-4-yl)urea

1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]-1-methyl-3-(2-methylphenyl)urea

3-(2-chlorophenyl)-1-(4-fluorophenyl)-1-[2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]urea

1-[4-(dimethylamino)phenyl]-3-(2-methylphenyl)-1-[2-[[(1S)-1-phenylethyl]amino]pyrimidin-4-yl]urea

1-(4-fluorophenyl)-1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea

1-amino-3-(2-chlorophenyl)-1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]urea