Brief Information of the Compound and Protein
Compound Name
[5-amino-1-(2,4-difluorophenyl)-1H-pyrazol-4-yl]-[3-(1-oxypyridin-3-yl)phenyl]methanone
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PubChem ID
CID: 11618088
SID: 16721014
Canonical SMILES
Nc1c(C(=O)c2cccc(-c3ccc[n+]([O-])c3)c2)cnn1-c1ccc(F)cc1F
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Compound Formula C21H14F2N4O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 340 nM