Brief Information of the Compound and Protein
Compound Name
3-(2-chlorophenyl)-1-[2-[[(2S)-3-hydroxy-3-methylbutan-2-yl]amino]pyrimidin-4-yl]-1-phenylurea
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PubChem ID
CID: 11575475
SID: 16677825
Canonical SMILES
C[C@H](Nc1nccc(n1)N(C(=O)Nc1ccccc1Cl)c1ccccc1)C(C)(C)O
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Compound Formula C22H24ClN5O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase MAPK family
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CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 718 nM
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