Brief Information of the Compound and Protein
Compound Name
4-{[3-(2-aminoethyl)phenyl]carbonyl}-1-(4-fluorophenyl)-1H-pyrazol-5-amine
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PubChem ID
CID: 11566683
SID: 16704989
Canonical SMILES
NCCc1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1
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Compound Formula C18H17FN4O
Compound Structure
Protein Name
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 520 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2440 nM