Brief Information of the Compound and Protein
Compound Name
3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)prop-2-yn-1-ol
    Show/Hide
PubChem ID
CID: 11508284
SID: 16610216
Canonical SMILES
Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C#CCO
    Show/Hide
Compound Formula C19H14FN3O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4040 nM