Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-(1-tert-butylpiperidin-4-yloxy)-5-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)quinolin-2(1H)-one
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 PubChem ID
CID: 44405934
Canonical SMILES
CC(C)(C)N1CCC(CC1)Oc1cc(-c2ccc(F)cc2F)c2ccc(=O)n(-c3c(F)cccc3F)c2c1
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Compound Formula C30H28F4N2O2
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10.5 nM