Brief Information of the Compound and Protein
Compound Name
1-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)ethane-1,2-diol
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PubChem ID
CID: 9949860
SID: 14924877
Canonical SMILES
Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C(O)CO
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Compound Formula C18H16FN3O3
Compound Structure
Protein Name
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3500 nM