Brief Information of the Compound and Protein
Compound Name
3-(2-chlorophenyl)-1-[4-(dimethylamino)phenyl]-1-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]urea
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PubChem ID
CID: 44412816
Canonical SMILES
COC[C@H](C)Nc1nccc(n1)N(C(=O)Nc1ccccc1Cl)c1ccc(cc1)N(C)C
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Compound Formula C23H27ClN6O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
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Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
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CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 > 5000 nM
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