| Compound ID |
Compound Name |
Compound Formula |
|
CP0287466
|
2-{3-[2-(2-chloro-4-hydroxyphenyl)-1,3-thiazol-5-yl]propanamido}benzoic acid
Show/Hide
|
C19H15ClN2O4S
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0377022
|
(4S,5R)-2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-4-methyl-5-(2,3,5-trifluorophenyl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C24H21F3N4O5
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
IC50 = 12 nM
|
|
|
|
CP0201083
|
2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C21H20N2O5
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
|
CP0388668
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)-5-propylcyclohex-1-enecarboxylic acid
Show/Hide
|
C23H27NO4
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0374155
|
5-(3,5-difluorophenyl)-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C26H23F2NO4
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0039221
|
2-({3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]-2,2-dimethylpropanoyl}-amino)cyclohex-1-ene-1-carboxylic acid
Show/Hide
|
C19H22N4O5
|
3
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
| 3 |
Ki = 595 nM
|
|
|
|
CP0374253
|
2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-5-propylcyclohex-1-enecarboxylic acid
Show/Hide
|
C20H24N4O5
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0294222
|
2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-3-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C21H22N2O5
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0039198
|
2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C17H18N4O5
|
5
|
| 1 |
EC50 = 21 nM
|
|
|
| 2 |
EC50 = 24 nM
|
|
|
| 3 |
IC50 = 4 nM
|
|
|
| 4 |
Ki = 3 nM
|
|
|
| 5 |
Ki = 150 nM
|
|
|
|
CP0495809
|
5-(3,5-difluorophenyl)-2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C23H19F3N4O4
|
2
|
| 1 |
EC50 = 22 nM
|
|
|
| 2 |
IC50 = 19 nM
|
|
|
|
CP0329426
|
2-(3-(6-fluoro-7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C21H19FN2O5
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0037107
|
hydron;pyridine-3-carboxylate
Show/Hide
|
C6H5NO2
|
11
|
| 1 |
EC50 = 26.92 nM
|
|
|
| 2 |
EC50 = 47 nM
|
|
|
| 3 |
EC50 = 527 nM
|
|
|
| 4 |
EC50 = 580 nM
|
|
|
| 5 |
EC50 = 1000 nM
|
|
|
| 6 |
EC50 = 1400 nM
|
|
|
| 7 |
IC50 = 130 nM
|
|
|
| 8 |
IC50 = 140 nM
|
|
|
| 9 |
IC50 = 67300 nM
|
|
|
| 10 |
Ki = 82 nM
|
|
|
| 11 |
Ki = 104 nM
|
|
|
|
CP0181338
|
2-{3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanamido}benzoic acid
Show/Hide
|
C17H14N4O5
|
3
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
| 3 |
Ki = 120 nM
|
|
|
|
CP0507807
|
5-(3-fluorophenyl)-2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C23H21FN4O5
|
2
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
|
CP0454212
|
5-(3-fluorophenyl)-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C26H24FNO4
|
2
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
IC50 = 7.4 nM
|
|
|
|
CP0374250
|
5-butyl-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C24H29NO4
|
2
|
| 1 |
EC50 = 30 nM
|
|
|
| 2 |
IC50 = 6 nM
|
|
|
|
CP0504353
|
5-(2-fluorophenyl)-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C26H24FNO4
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0294219
|
2-(3-(7-hydroxy-2H-benzo[g]indazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C21H17N3O4
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0315869
|
(R)-2-(2-amino-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)benzoic acid
Show/Hide
|
C17H15N5O5
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0164311
|
(S)-2-(2-amino-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C17H19N5O5
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0372211
|
2-(3-(7-hydroxy-[1,2,3]triazolo[1,5-a]quinolin-3-yl)propanamido)benzoic acid
Show/Hide
|
C20H16N4O4
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0487697
|
(4S,5R)-5-(3-fluorophenyl)-2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-4-methylcyclohex-1-enecarboxylic acid
Show/Hide
|
C24H23FN4O5
|
2
|
| 1 |
EC50 = 42 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0322480
|
2-(3-(6-chloro-7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C21H19ClN2O5
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0103559
|
2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanamido}benzoic acid
Show/Hide
|
C22H18ClNO4
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0373441
|
2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-5-(2,3,5-trifluorophenyl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C23H18F4N4O4
|
2
|
| 1 |
EC50 = 45 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0374256
|
2-(2-amino-3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-5-(2,3,5-trifluorophenyl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C23H19F4N5O4
|
2
|
| 1 |
EC50 = 46 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0294223
|
2-(3-(7-hydroxypyrazolo[1,5-a]quinolin-3-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C21H21N3O4
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0191723
|
2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C21H18N2O5
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0307464
|
2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C21H16N2O5
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0136308
|
(S)-2-(2-amino-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)benzoic acid
Show/Hide
|
C17H15N5O5
|
1
|
| 1 |
EC50 < 52 nM
|
|
|
|
CP0287385
|
2-(3-(4'-hydroxybiphenyl-4-yl)propanamido)benzoic acid
Show/Hide
|
C22H19NO4
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0294220
|
2-(3-(7-hydroxy-4,5-dihydropyrazolo[1,5-a]quinolin-3-yl)propanamido)benzoic acid
Show/Hide
|
C21H19N3O4
|
1
|
| 1 |
EC50 = 64 nM
|
|
|
|
CP0388671
|
5-(6-fluoropyridin-3-yl)-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C25H23FN2O4
|
2
|
| 1 |
EC50 = 64 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0161431
|
2-(3-(7-hydroxy-4,5-dihydropyrazolo[1,5-a]quinolin-2-yl)propanamido)benzoic acid
Show/Hide
|
C21H19N3O4
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0307463
|
2-(3-(7-hydroxy-4,5-dihydro-2H-benzo[g]indazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C21H19N3O4
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0374249
|
(4S,5R)-2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-4-methyl-5-(2,3,5-trifluorophenyl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C24H20F4N4O4
|
2
|
| 1 |
EC50 = 75 nM
|
|
|
| 2 |
IC50 = 6 nM
|
|
|
|
CP0294224
|
2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-propionylamino]-cyclohex-1-enecarboxylic acid
Show/Hide
|
C19H19N3O4S
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
|
CP0384940
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C20H21NO4
|
2
|
| 1 |
EC50 = 76 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0252493
|
2-{3-[5-(2-chloro-4-hydroxyphenyl)thiophen-2-yl]propanamido}benzoic acid
Show/Hide
|
C20H16ClNO4S
|
1
|
| 1 |
EC50 = 77 nM
|
|
|
|
CP0049193
|
(R)-2-((S)-2-amino-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-4-methylcyclohex-1-enecarboxylic acid
Show/Hide
|
C18H21N5O5
|
1
|
| 1 |
EC50 = 85 nM
|
|
|
|
CP0038785
|
2-{3-[4-(5-hydroxypyridin-2-yl)phenyl]propanamido}benzoic acid
Show/Hide
|
C21H18N2O4
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0402253
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)-5-phenylcyclohex-1-enecarboxylic acid
Show/Hide
|
C26H25NO4
|
2
|
| 1 |
EC50 = 92 nM
|
|
|
| 2 |
IC50 = 34 nM
|
|
|
|
CP0240443
|
2-{3-[1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-4-yl]propanamido}benzoic acid
Show/Hide
|
C20H19N3O4
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
|
CP0504354
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)-5-(6-(trifluoromethyl)pyridin-3-yl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C26H23F3N2O4
|
2
|
| 1 |
EC50 = 94 nM
|
|
|
| 2 |
IC50 = 18 nM
|
|
|
|
CP0490787
|
5-(6-fluoropyridin-3-yl)-2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C22H20FN5O5
|
2
|
| 1 |
EC50 = 98 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0374248
|
2-(2-amino-3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-5-(3,5-difluorophenyl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C23H20F3N5O4
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
|
CP0254561
|
2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-3-yl)propanamido)cyclopent-1-enecarboxylic acid
Show/Hide
|
C20H20N2O5
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0229178
|
2-{3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanamido}benzoic acid
Show/Hide
|
C18H15N3O5
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0254560
|
2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-propionylamino]-benzoic acid
Show/Hide
|
C19H15N3O4S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0398279
|
3-(benzylamino)-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C11H11N3O2
|
1
|
| 1 |
EC50 = 120.23 nM
|
|
|
|
CP0487705
|
5-(4-fluorophenyl)-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C26H24FNO4
|
2
|
| 1 |
EC50 = 130 nM
|
|
|
| 2 |
IC50 = 8.6 nM
|
|
|
|
CP0490762
|
5-(2-fluoropyridin-3-yl)-2-(3-(4'-hydroxybiphenyl-4-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C27H25FN2O4
|
2
|
| 1 |
EC50 = 137 nM
|
|
|
| 2 |
IC50 = 36 nM
|
|
|
|
CP0377380
|
(+)-acifran
Show/Hide
|
C12H10O4
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0254559
|
2-(3-(7-hydroxy-2-methyl-4,5-dihydro-2H-benzo[g]indazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C22H21N3O4
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0049194
|
(R)-2-((S)-2-amino-3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-4-methylcyclohex-1-enecarboxylic acid
Show/Hide
|
C18H20FN5O4
|
1
|
| 1 |
EC50 = 214 nM
|
|
|
|
CP0454249
|
5-(3-fluorophenyl)-2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C23H20F2N4O4
|
2
|
| 1 |
EC50 = 230 nM
|
|
|
| 2 |
IC50 = 57 nM
|
|
|
|
CP0229176
|
2-{3-[2-(4-hydroxy-1H-pyrazol-1-yl)-1,3-thiazol-5-yl]propanamido}benzoic acid
Show/Hide
|
C16H14N4O4S
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0507249
|
2-(2-amino-3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-5-(3-fluorophenyl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C23H21F2N5O4
|
2
|
| 1 |
EC50 = 250 nM
|
|
|
| 2 |
IC50 = 85 nM
|
|
|
|
CP0294221
|
2-(3-(3H-benzo[e]indazol-7-yl)propanamido)benzoic acid
Show/Hide
|
C21H17N3O3
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0382784
|
2-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]butanoylamino]cyclohexene-1-carboxylic acid
Show/Hide
|
C18H20N4O5
|
3
|
| 1 |
EC50 = 290 nM
|
|
|
| 2 |
Ki = 29 nM
|
|
|
| 3 |
Ki = 1100 nM
|
|
|
|
CP0502657
|
2-[[2-hydroxy-3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid
Show/Hide
|
C17H18N4O6
|
3
|
| 1 |
EC50 = 290 nM
|
|
|
| 2 |
Ki = 22 nM
|
|
|
| 3 |
Ki = 660 nM
|
|
|
|
CP0161434
|
(S)-2-(2-amino-3-(3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl)propanamido)benzoic acid
Show/Hide
|
C18H16N4O5
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0191725
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)benzoic acid
Show/Hide
|
C20H17NO4
|
3
|
| 1 |
EC50 = 340 nM
|
|
|
| 2 |
EC50 = 380 nM
|
|
|
| 3 |
IC50 = 24 nM
|
|
|
|
CP0374259
|
5-(2-fluoropyridin-3-yl)-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C25H23FN2O4
|
2
|
| 1 |
EC50 = 410 nM
|
|
|
| 2 |
IC50 = 52 nM
|
|
|
|
CP0207509
|
(R)-2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-4-methylcyclohex-1-enecarboxylic acid
Show/Hide
|
C18H19FN4O4
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0103932
|
2-{3-[2-(5-hydroxypyridin-2-yl)-1,3-thiazol-5-yl]propanamido}benzoic acid
Show/Hide
|
C18H15N3O4S
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0407033
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)-5-methylcyclohex-1-enecarboxylic acid
Show/Hide
|
C21H23NO4
|
2
|
| 1 |
EC50 = 430 nM
|
|
|
| 2 |
IC50 = 43 nM
|
|
|
|
CP0374254
|
2-(2-amino-3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C17H18FN5O4
|
2
|
| 1 |
EC50 = 460 nM
|
|
|
| 2 |
IC50 = 32 nM
|
|
|
|
CP0374260
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)-5-(1-methyl-1H-pyrazol-5-yl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C24H25N3O4
|
2
|
| 1 |
EC50 = 480 nM
|
|
|
| 2 |
IC50 = 14 nM
|
|
|
|
CP0377028
|
2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C17H17FN4O4
|
2
|
| 1 |
EC50 = 490 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
|
CP0340840
|
2-[3-(naphthalen-2-yl)propanamido]benzoic acid
Show/Hide
|
C20H17NO3
|
3
|
| 1 |
EC50 = 500 nM
|
|
|
| 2 |
EC50 = 1000 nM
|
|
|
| 3 |
IC50 = 140 nM
|
|
|
|
CP0164310
|
2-((2S)-2-amino-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)butanamido)benzoic acid
Show/Hide
|
C18H17N5O5
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0428562
|
2-(3-(6-aminonaphthalen-2-yl)propanamido)benzoic acid
Show/Hide
|
C20H18N2O3
|
2
|
| 1 |
EC50 = 540 nM
|
|
|
| 2 |
IC50 = 34 nM
|
|
|
|
CP0369318
|
2-[3-(4-phenylphenyl)propanamido]benzoic acid
Show/Hide
|
C22H19NO3
|
1
|
| 1 |
EC50 = 590 nM
|
|
|
|
CP0035622
|
2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl)-propionylamino]-cyclopent-1-enecarboxylic acid
Show/Hide
|
C18H17N3O4S
|
1
|
| 1 |
EC50 = 620 nM
|
|
|
|
CP0351956
|
2-(3-Benzo[d]imidazo[2,1-b]thiazol-2-yl-propionylamino)-benzoic acid
Show/Hide
|
C19H15N3O3S
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0294084
|
2-((S)-2-amino-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-5-methylcyclohex-1-enecarboxylic acid
Show/Hide
|
C18H21N5O5
|
1
|
| 1 |
EC50 = 721 nM
|
|
|
|
CP0373763
|
2-(1-((3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)methyl)cyclobutanecarboxamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C20H22N4O5
|
3
|
| 1 |
EC50 = 730 nM
|
|
|
| 2 |
Ki = 360 nM
|
|
|
| 3 |
Ki = 1080 nM
|
|
|
|
CP0330105
|
2-(3-(7-hydroxy-1-methyl-4,5-dihydro-1H-benzo[g]indazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C22H21N3O4
|
1
|
| 1 |
EC50 = 840 nM
|
|
|
|
CP0207438
|
(R)-2-(2-amino-3-(3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl)propanamido)benzoic acid
Show/Hide
|
C18H16N4O5
|
1
|
| 1 |
EC50 = 890 nM
|
|
|
|
CP0044111
|
5-methyl-1H-pyrazole-3-carboxylic acid
Show/Hide
|
C5H6N2O2
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0340839
|
2-{3-[5-(5-hydroxypyridin-2-yl)-1,3-thiazol-2-yl]propanamido}benzoic acid
Show/Hide
|
C18H15N3O4S
|
1
|
| 1 |
EC50 = 930 nM
|
|
|
|
CP0291486
|
2-(2-amino-3-(2-(2-chloro-4-hydroxyphenyl)thiazol-5-yl)propanamido)benzoic acid
Show/Hide
|
C19H16ClN3O4S
|
1
|
| 1 |
EC50 = 930 nM
|
|
|
|
CP0428551
|
2-(3-(6-formylnaphthalen-2-yl)propanamido)benzoic acid
Show/Hide
|
C21H17NO4
|
2
|
| 1 |
EC50 = 940 nM
|
|
|
| 2 |
IC50 = 55 nM
|
|
|
|
CP0038784
|
2-{3-[4-(pyridin-2-yl)phenyl]propanamido}benzoic acid
Show/Hide
|
C21H18N2O3
|
1
|
| 1 |
EC50 = 970 nM
|
|
|
|
CP0452499
|
2-(5-(naphthalen-2-yl)pentanamido)benzoic acid
Show/Hide
|
C22H21NO3
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0310515
|
2-(2-amino-3-(7-hydroxy-4,5-dihydropyrazolo[1,5-a]quinolin-2-yl)propanamido)benzoic acid
Show/Hide
|
C21H20N4O4
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0201484
|
(+/-)-5-(2,3,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
Show/Hide
|
C14H11F3N2O2
|
2
|
| 1 |
EC50 = 1100 nM
|
|
|
| 2 |
IC50 = 67 nM
|
|
|
|
CP0914677
|
5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrobromide
Show/Hide
|
C14H13BrF2N2O2
|
3
|
| 1 |
EC50 = 1100 nM
|
|
|
| 2 |
IC50 = 90 nM
|
|
|
| 3 |
IC50 = 400 nM
|
|
|
|
CP0490839
|
2-(2-(4-tert-butylphenoxy)acetamido)benzoic acid
Show/Hide
|
C19H21NO4
|
2
|
| 1 |
EC50 = 1200 nM
|
|
|
| 2 |
IC50 = 1200 nM
|
|
|
|
CP0103561
|
2-{3-[1-(5-hydroxypyridin-2-yl)-1H-pyrazol-3-yl]propanamido}benzoic acid
Show/Hide
|
C18H16N4O4
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0230942
|
(+/-)-5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
Show/Hide
|
C14H12F2N2O2
|
2
|
| 1 |
EC50 = 1300 nM
|
|
|
| 2 |
IC50 = 220 nM
|
|
|
|
CP0497474
|
(+/-)-5-(2,5-difluorophenyl)-3-(1H-tetrazol-5-yl)-4,5,6,7-tetrahydro-1H-indazole
Show/Hide
|
C14H12F2N6
|
2
|
| 1 |
EC50 = 1300 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0049191
|
(S)-2-(3-(3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl)-2-(methylamino)propanamido)benzoic acid
Show/Hide
|
C19H18N4O5
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0103925
|
2-{3-[4-(1H-pyrrol-2-yl)phenyl]propanamido}benzoic acid
Show/Hide
|
C20H18N2O3
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0888647
|
5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrobromide
Show/Hide
|
C13H13BrFN3O2
|
3
|
| 1 |
EC50 = 2300 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
| 3 |
IC50 = 370 nM
|
|
|
|
CP0428835
|
(+/-)-5-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
Show/Hide
|
C14H13ClN2O2
|
2
|
| 1 |
EC50 = 2500 nM
|
|
|
| 2 |
IC50 = 460 nM
|
|
|
|
CP0329425
|
2-(3-(8-hydroxy-5-methyl-6-oxo-5,6-dihydrophenanthridin-3-yl)propanamido)benzoic acid
Show/Hide
|
C24H20N2O5
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0374251
|
2-(3-(6-hydroxynaphthalen-2-yl)propanamido)-5-(1-methyl-1H-pyrazol-4-yl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C24H25N3O4
|
2
|
| 1 |
EC50 = 2650 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0207508
|
(R)-2-(3-amino-3-(3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl)propanamido)benzoic acid
Show/Hide
|
C18H16N4O5
|
1
|
| 1 |
EC50 = 2960 nM
|
|
|
|
CP0271840
|
(S)-2-(2-amino-3-(4'-hydroxybiphenyl-4-yl)propanamido)benzoic acid
Show/Hide
|
C22H20N2O4
|
1
|
| 1 |
EC50 = 3200 nM
|
|
|
|
CP0879629
|
2-(3-(4-(3,5-dimethylisoxazol-4-yl)phenyl)propanamido)benzoic acid
Show/Hide
|
C21H20N2O4
|
1
|
| 1 |
EC50 = 3400 nM
|
|
|
|
CP0049190
|
(S)-2-(3-amino-3-(3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl)propanamido)benzoic acid
Show/Hide
|
C18H16N4O5
|
1
|
| 1 |
EC50 = 3420 nM
|
|
|
|
CP0336159
|
(+/-)-5-(2-fluoropyridin-3-yl)-3-(1H-tetrazol-5-yl)-4,5,6,7-tetrahydro-1H-indazole
Show/Hide
|
C13H12FN7
|
2
|
| 1 |
EC50 = 3800 nM
|
|
|
| 2 |
IC50 = 500 nM
|
|
|
|
CP0396987
|
(+/-)-5-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
Show/Hide
|
C14H13FN2O2
|
2
|
| 1 |
EC50 = 4400 nM
|
|
|
| 2 |
IC50 = 270 nM
|
|
|
|
CP0452576
|
(+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
Show/Hide
|
C13H12FN3O2
|
3
|
| 1 |
EC50 = 4500 nM
|
|
|
| 2 |
IC50 = 600 nM
|
|
|
| 3 |
IC50 = 850 nM
|
|
|
|
CP0504352
|
5-cyano-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C21H20N2O4
|
1
|
| 1 |
EC50 = 5300 nM
|
|
|
|
CP0880109
|
5-(2-fluoropyridin-3-yl)-3-(1H-tetrazol-5-yl)-4,5,6,7-tetrahydro-1H-indazole, hydrobromide
Show/Hide
|
C13H11BrFN7
|
2
|
| 1 |
EC50 = 5500 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0079784
|
2-[2-(4-methoxyphenoxy)acetamido]benzoic acid
Show/Hide
|
C16H15NO5
|
2
|
| 1 |
EC50 = 6000 nM
|
|
|
| 2 |
EC50 = 12500 nM
|
|
|
|
CP0382786
|
2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)-3-methylbutanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C19H22N4O5
|
3
|
| 1 |
EC50 = 6400 nM
|
|
|
| 2 |
Ki = 130 nM
|
|
|
| 3 |
Ki = 24700 nM
|
|
|
|
CP0336173
|
2-(3-(6-hydroxy-1-methyl-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C21H19N3O4
|
1
|
| 1 |
EC50 = 7300 nM
|
|
|
|
CP0373443
|
2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-5-(6-fluoropyridin-3-yl)cyclohex-1-enecarboxylic acid
Show/Hide
|
C22H19F2N5O4
|
2
|
| 1 |
EC50 = 7400 nM
|
|
|
| 2 |
IC50 = 280 nM
|
|
|
|
CP0398282
|
3-[bis(thiophen-3-ylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C14H13N3O2S2
|
1
|
| 1 |
EC50 = 9120.11 nM
|
|
|
|
CP0377767
|
3-[bis[(3-fluorophenyl)methyl]amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C18H15F2N3O2
|
1
|
| 1 |
EC50 = 9332.54 nM
|
|
|
|
CP0398993
|
3-[thiophen-2-ylmethyl(thiophen-3-ylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C14H13N3O2S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0404731
|
3-[bis(3-methylbutyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C14H25N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421481
|
3-[bis(2-phenylethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C20H21N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421482
|
3-(dihexylamino)-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C16H29N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421483
|
3-(dipropylamino)-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C10H17N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0439735
|
3-[bis[(5-bromothiophen-2-yl)methyl]amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C14H11Br2N3O2S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0480372
|
3-[furan-3-ylmethyl(thiophen-3-ylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C14H13N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0480373
|
3-[(4-fluorophenyl)methyl-(thiophen-3-ylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C16H14FN3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0480374
|
3-[benzyl(thiophen-3-ylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C16H15N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0480375
|
3-[bis[(5-methylthiophen-2-yl)methyl]amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C16H17N3O2S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0480379
|
3-[bis(cyclohexylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C18H29N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0492694
|
3-(dibenzylamino)-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0505741
|
3-[furan-2-ylmethyl(thiophen-3-ylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C14H13N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0514120
|
3-[bis(thiophen-2-ylmethyl)amino]-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C14H13N3O2S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0035621
|
2-(3-(6-hydroxy-4H-indeno[2,1-d]isoxazol-3-yl)propanamido)benzoic acid
Show/Hide
|
C20H16N2O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0463929
|
6-(pentan-3-ylamino)nicotinic acid
Show/Hide
|
C11H16N2O2
|
1
|
| 1 |
EC50 = 20000 nM
|
|
|
|
CP0092831
|
2-{3-[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]propanamido}benzoic acid
Show/Hide
|
C18H15N3O5
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0939737
|
2-(3-(4-(5-aminopyridin-2-yl)phenyl)propanamido)benzoic acid
Show/Hide
|
C21H19N3O3
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0422003
|
(+/-)-5-phenyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
Show/Hide
|
C14H14N2O2
|
1
|
| 1 |
EC50 = 28000 nM
|
|
|
|
CP0503880
|
6-(isobutylamino)nicotinic acid
Show/Hide
|
C10H14N2O2
|
1
|
| 1 |
EC50 = 35000 nM
|
|
|
|
CP0458321
|
2-(3-(7-hydroxy-5-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]quinoxalin-3-yl)propanamido)benzoic acid
Show/Hide
|
C20H17N5O5
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0849219
|
8-chloro-1-propyl-3-(2,2,2-trifluoroethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H10ClF3N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0849220
|
8-chloro-1-ethyl-3-(2,2,2-trifluoroethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C9H8ClF3N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0849221
|
8-Chloro-3-(4-penten-1-yl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H11ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0849551
|
8-chloro-1,3-bis(4,4,4-trifluorobutyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C13H13ClF6N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0858040
|
8-chloro-1-methyl-3-pentyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0858042
|
[8-chloro-3-(2-cyclopropylethyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl]acetonitrile
Show/Hide
|
C12H12ClN5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0858043
|
1,3-dibutyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purine-8-carbonitrile
Show/Hide
|
C14H19N5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0858044
|
8-chloro-3-(3-methylbutyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H13ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0859840
|
8-chloro-3-(6-methylheptyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C13H19ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0861993
|
3-butyl-8-chloro-1-ethyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0861994
|
8-Chloro-3-(cyclopropylmethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C9H9ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0861995
|
8-chloro-3-(3-cyclopropylpropyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H13ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0865036
|
3-(3-buten-1-yl)-8-chloro-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C9H9ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0865037
|
(+/-)-8-Chloro-3-(3-methylpentyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0865038
|
8-chloro-3-(2-cyclopropylethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H11ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0866088
|
8-Chloro-3-decyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C15H23ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0866089
|
8-chloro-1-methyl-3-propyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C9H11ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0866090
|
8-Chloro-3-hexyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0867462
|
8-Bromo-1-methyl-3-pentyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H15BrN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0867464
|
8-Chloro-3-octyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C13H19ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0867465
|
8-Chloro-3-(4-methylpentyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0867466
|
8-chloro-3-(4,4,4-trifluorobutyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C9H8ClF3N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0880975
|
8-chloro-3-(4-fluorobutyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C9H10ClFN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0880976
|
8-chloro-1-methyl-3-(4,4,4-trifluorobutyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H10ClF3N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0880977
|
(8-chloro-2,6-dioxo-1,2,6,7-tetrahydro-3H-purin-3-yl)acetonitrile
Show/Hide
|
C7H4ClN5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0880978
|
8-chloro-3-(3,3,3-trifluoropropyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C8H6ClF3N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0896475
|
2,2'-(8-chloro-2,6-dioxo-6,7-dihydro-1H-purine-1,3(2H)-diyl)diacetonitrile
Show/Hide
|
C9H5ClN6O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0896539
|
4-(8-chloro-2,6-dioxo-1,2,6,7-tetrahydro-3H-purin-3-yl)butanenitrile
Show/Hide
|
C9H8ClN5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0900472
|
3-butyl-8-chloro-1-methyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H13ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0902186
|
(3-butyl-8-chloro-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetonitrile
Show/Hide
|
C11H12ClN5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0902187
|
8-Chloro-3-propyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C8H9ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0903239
|
(8-chloro-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-1H-purin-1-yl)acetonitrile
Show/Hide
|
C10H10ClN5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0904296
|
(+/-)-8-Chloro-3-(2-methylbutyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H13ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0904358
|
8-chloro-3-(cyclopentylmethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H13ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0904363
|
(+/-)-8-Chloro-3-(2-methylpentyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0904364
|
4-(8-chloro-1-methyl-2,6-dioxo-1,2,6,7-tetrahydro-3H-purin-3-yl)butanenitrile
Show/Hide
|
C10H10ClN5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0931096
|
8-chloro-3-pentyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H13ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0931097
|
8-chloro-3-(5-fluoropentyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H12ClFN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0935583
|
3-butyl-1-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purine-8-carbonitrile
Show/Hide
|
C11H13N5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0940829
|
8-chloro-3-(3-fluoropropyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C8H8ClFN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0940839
|
8-chloro-3-(6-fluorohexyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H14ClFN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0940850
|
8-chloro-3-hexyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C12H17ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0940851
|
8-chloro-3-(2,2,2-trifluoroethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C7H4ClF3N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0945618
|
1-Methyl-2,6-dioxo-3-pentyl-2,3,6,7-tetrahydro-1H-purine-8-carbonitrile
Show/Hide
|
C12H15N5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0946751
|
8-chloro-3-ethyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C8H9ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0950350
|
8-Chloro-3-(cyclohexylmethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C12H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0950351
|
8-chloro-3-(2-cyclobutylethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H13ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0951284
|
8-Chloro-3-(cyclobutylmethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C10H11ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0951285
|
8-Chloro-3-(2-cyclopentylethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C12H15ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0951848
|
8-chloro-1-(4,4,4-trifluorobutyl)-3-(2,2,2-trifluoroethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C11H9ClF6N4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0952105
|
6-(8-Chloro-2,6-dioxo-1,2,6,7-tetrahydro-3H-purin-3-yl)-2,2-dimethylhexanenitrile
Show/Hide
|
C13H16ClN5O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0953065
|
1,3-dibutyl-8-iodo-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C13H19IN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0953531
|
8-chloro-3-(2-cyclohexylethyl)-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C13H17ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0954857
|
3-butyl-8-chloro-3,7-dihydro-1H-purine-2,6-dione
Show/Hide
|
C9H11ClN4O2
|
1
|
| 1 |
EC50 < 12589.25 nM
|
|
|
|
CP0486796
|
2-(3-(6-methoxynaphthalen-2-yl)propanamido)benzoic acid
Show/Hide
|
C21H19NO4
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0377026
|
5-hydroxy-2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C20H21NO5
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0464335
|
3-methyl-5-carboxyl-isoxazole
Show/Hide
|
C5H5NO3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0461239
|
3-(3-bromobenzyl)-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C11H9BrN2O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0412823
|
3-(3-fluorobenzyl)-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C11H9FN2O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0436695
|
3-isopropyl-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C7H10N2O2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0412826
|
3-(3-chlorobenzyl)-1H-pyrazole-5-carboxylic acid
Show/Hide
|
C11H9ClN2O2
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0421435
|
(+/-)-5-(2,6-difluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
Show/Hide
|
C14H12F2N2O2
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0447397
|
2-(2,2,3,3-tetrafluoro-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C17H14F4N4O5
|
2
|
| 1 |
Ki = 1.4 nM
|
|
|
| 2 |
Ki = 840 nM
|
|
|
|
CP0526337
|
2-(1-((3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)methyl)cyclopropanecarboxamido)cyclohex-1-enecarboxylic acid
Show/Hide
|
C19H20N4O5
|
2
|
| 1 |
Ki = 11 nM
|
|
|
| 2 |
Ki = 9130 nM
|
|
|
