Brief Information of the Compound and Protein
Compound Name
2-(2,2,3,3-tetrafluoro-3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
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PubChem ID
CID: 135887290
SID: 93369942
Canonical SMILES
OC(=O)C1=C(CCCC1)NC(=O)C(F)(F)C(F)(F)c1nc(no1)-c1ccc(O)cn1
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Compound Formula C17H14F4N4O5
Compound Structure
Protein Name
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS
2
Ki = 840 nM
   TI
   LI
   LO
   TS