Brief Information of the Compound and Protein
Compound Name
5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrobromide
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PubChem ID
CID: 52947887
Canonical SMILES
Br.O=C(O)c1n[nH]c2c1CC(c1cccnc1F)CC2
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Compound Formula C13H13BrFN3O2
Compound Structure
Protein Name
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  3
1
EC50 = 2300 nM
   TI
   LI
   LO
   TS
2
IC50 = 200 nM
   TI
   LI
   LO
   TS
3
IC50 = 370 nM
   TI
   LI
   LO
   TS