Brief Information of the Compound and Protein
Compound Name
2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propanamido)benzoic acid
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PubChem ID
SID: 81057654
Canonical SMILES
OC(=O)c1ccccc1NC(=O)CCc1noc2c1ccc1cc(O)ccc21
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Compound Formula C21H16N2O5
Compound Structure
Protein Name
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 51 nM
   TI
   LI
   LO
   TS