Brief Information of the Compound and Protein
Compound Name
(4S,5R)-2-(3-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)-4-methyl-5-(2,3,5-trifluorophenyl)cyclohex-1-enecarboxylic acid
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PubChem ID
CID: 46890580
Canonical SMILES
C[C@H]1CC(NC(=O)CCc2nc(no2)-c2ccc(F)cn2)=C(C[C@H]1c1cc(F)cc(F)c1F)C(O)=O
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Compound Formula C24H20F4N4O4
Compound Structure
Protein Name
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 75 nM
   TI
   LI
   LO
   TS
2
IC50 = 6 nM
   TI
   LI
   LO
   TS