Brief Information of the Compound and Protein
Compound Name
2-(3-(7-hydroxy-4,5-dihydro-2H-benzo[g]indazol-3-yl)propanamido)benzoic acid
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PubChem ID
CID: 135502978
SID: 16742708
Canonical SMILES
OC(=O)c1ccccc1NC(=O)CCc1[nH]nc-2c1CCc1cc(O)ccc-21
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Compound Formula C21H19N3O4
Compound Structure
Protein Name
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 74 nM
   TI
   LI
   LO
   TS