Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanamido)cyclohex-1-enecarboxylic acid
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 PubChem ID
CID: 135416388
SID: 24266202
Canonical SMILES
OC(=O)C1=C(CCCC1)NC(=O)CCc1nc(no1)-c1ccc(O)cn1
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Compound Formula C17H18N4O5
Compound Structure
Protein Name
 Protein Info 
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Carboxylic acid receptor
>
Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  5
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
2
EC50 = 24 nM
   TI
   LI
   LO
   TS
3
IC50 = 4 nM
   TI
   LI
   LO
   TS
4
Ki = 3 nM
   TI
   LI
   LO
   TS
5
Ki = 150 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM