Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanamido}benzoic acid
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 PubChem ID
CID: 11560300
SID: 16662562
Canonical SMILES
OC(=O)c1ccccc1NC(=O)CCc1ccc(cc1)-c1ccc(O)cc1Cl
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Compound Formula C22H18ClNO4
Compound Structure
Protein Name
 Protein Info 
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 45 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 45 nM
2 IC50 = 4 nM