2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-ylamino)propane-1,3-diol

2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propan-1-ol

2-[[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]methyl]propane-1,3-diol

5-(5-ethynyl-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

3-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propane-1,2-diol

2-[[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]methyl]-2-methylpropane-1,3-diol

N-[2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]ethyl]acetamide

2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]ethanol

(R)-2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-ylamino)propan-1-ol

5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine

1-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propan-2-ol

3-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propan-1-ol

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-methylsulfonylethyl)pyrimidine-2,4-diamine

5-(5-bromo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-(5-chloro-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-(4,5-dimethoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

N-[(2R)-1-(4-acetylpiperazin-1-yl)propan-2-yl]-1-methyl-3-phenylthieno[2,3-c]pyrazole-5-carboxamide

5-(4-iodo-5-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-[4-methoxy-2-propan-2-yl-5-(2H-tetrazol-5-yl)phenoxy]pyrimidine-2,4-diamine

N-[1-(4-acetylpiperazin-1-yl)propan-2-yl]-1-methyl-3-(4-methylphenyl)thieno[2,3-c]pyrazole-5-carboxamide

N-[1-(4-acetylpiperazin-1-yl)propan-2-yl]-3-(2-fluorophenyl)-1-methylthieno[2,3-c]pyrazole-5-carboxamide

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-methylpyrimidine-2,4-diamine

5-(5-ethyl-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-piperazin-1-ylethyl)pyrimidine-2,4-diamine

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-methoxyethyl)pyrimidine-2,4-diamine

3-(2-fluorophenyl)-1-methyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2,2,2-trifluoroethyl)pyrimidine-2,4-diamine

5-(4-bromo-5-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(1-methylsulfonylpiperidin-4-yl)pyrimidine-2,4-diamine

2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]-2-methylpropan-1-ol

5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzamide

5-(4-methoxy-5-methyl-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-(4-methoxy-5-methylsulfonyl-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

N-[1-(4-ethanethioylpiperazin-1-yl)propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide

N-(1-(4-acetylpiperazin-1-yl)propan-2-yl)-1-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(oxan-4-yl)pyrimidine-2,4-diamine

5-[(4,5-dimethoxy-2-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine

3-(4-fluorophenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-morpholin-4-ylethyl)pyrimidine-2,4-diamine

2-N-[2-(dimethylamino)ethyl]-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-(2-ethyl-4,5-dimethoxyphenoxy)pyrimidine-2,4-diamine

5-[5-(1H-imidazol-2-yl)-4-methoxy-2-propan-2-ylphenoxy]pyrimidine-2,4-diamine

5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzoic acid

1-methyl-3-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide

2-N-(2-aminoethyl)-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine

2-phenyl-4-propyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

1-[2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]ethyl]piperidin-4-ol

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-4-amine

5-(5-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

3,5-bis(4-fluorophenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide

N-[(2R)-1-(4-acetylpiperazin-1-yl)propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide

5-[4-methoxy-2,5-di(propan-2-yl)phenoxy]pyrimidine-2,4-diamine

2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyrazin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

3-bromo-5-(4-fluorophenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide

3-(4-fluorophenyl)-5-propyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide

1-ethyl-3-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide

5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzonitrile

3,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]furan-2-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[1-[4-(1,3-thiazol-2-yl)piperazin-1-yl]propan-2-yl]-1,3-oxazole-5-carboxamide

5-(4-methoxy-5-phenyl-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

N-[(2R)-1-(4-carbamoylpiperazin-1-yl)propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide

1,3-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-4-carboxamide

2,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-3-carboxamide

5-[(2-cyclopropyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

2,4-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

1,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-3-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyrimidin-4-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

2,6-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyridine-4-carboxamide

5-[(2-ethyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

5-(4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyridin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

2,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]furan-3-carboxamide

2-methyl-1,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrrole-3-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[(2S)-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

1-methyl-3-(2-methylphenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-methylpyrimidin-4-amine

5-[4-(4-fluorophenyl)-5-methoxy-2-propan-2-ylphenoxy]pyrimidine-2,4-diamine

2-(4-fluorophenyl)-N-[(2R)-1-[4-(furan-2-carbonyl)piperazin-1-yl]propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[1-(4-pyrimidin-2-yl-1,4-diazepan-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

5-(5-fluoro-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

5-(2-propan-2-ylphenoxy)pyrimidine-2,4-diamine

2,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-4-carboxamide

4,6-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrimidine-2-carboxamide

4-methyl-2-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N,2-N-dimethylpyrimidine-2,4-diamine

5-[2-(2-ethyl-4,5-dimethoxyphenyl)ethyl]pyrimidine-2,4-diamine

(2,4-diaminopyrimidin-5-yl)-(4,5-dimethoxy-2-propan-2-ylphenyl)methanol

5-[(2-cyclobutyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

4-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-5-propan-2-ylbenzonitrile

5-[(2-tert-butyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

(2,4-diaminopyrimidin-5-yl)-(4,5-dimethoxy-2-propan-2-ylphenyl)methanone

5-[[4,5-dimethoxy-2-(2-methylpropyl)phenyl]methyl]pyrimidine-2,4-diamine

ORMETOPRIM

5-[5-(4,5-dihydro-1H-imidazol-2-yl)-4-methoxy-2-propan-2-ylphenoxy]pyrimidine-2,4-diamine

5-[(4,5-dimethoxy-2-propylphenyl)methyl]pyrimidine-2,4-diamine

N-[(2R)-1-[4-(cyclopropanecarbonyl)piperazin-1-yl]propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide

2-(4-fluorophenyl)-N-[(2R)-1-[4-(methylcarbamoyl)piperazin-1-yl]propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide

2,4-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-thiazole-5-carboxamide

2-(4-fluorophenyl)-N-[(2R)-1-(4-methylsulfonylpiperazin-1-yl)propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[1-(4-pyridin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

ethyl 4-[(2R)-2-[[2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carbonyl]amino]propyl]piperazine-1-carboxylate

5-methyl-1,3-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-4-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyridin-4-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide

1,3-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide

2-(4-fluorophenyl)-N-[2-methyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide

1-(4-fluorophenyl)-3-phenyl-5-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-6H-pyrrolo[3,4-c]pyrazol-4-one

1-methyl-3-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]furo[2,3-c]pyrazole-5-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]-1,3-oxazole-5-carboxamide

2-(4-fluorophenyl)-4-propyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)butan-2-yl]-1,3-oxazole-5-carboxamide

2-(4-fluorophenyl)-N-methyl-4-propyl-N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]-1,3-oxazole-5-carboxamide

2-(4-fluorophenyl)-4-propyl-5-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yloxymethyl]-1,3-oxazole

3-methyl-1-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide

N-[[2-(4-fluorophenyl)-4-propyl-1,3-oxazol-5-yl]methyl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-amine