General Information of the Compound
Compound ID
CP0417944
Compound Name
2-(4-fluorophenyl)-4-propyl-N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]-1,3-oxazole-5-carboxamide
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Structure
Formula
C23H27FN6O2
Molecular Weight
438.507
Canonical SMILES
CCCc1nc(oc1C(=O)NCCN1CCN(CC1)c1ncccn1)-c1ccc(F)cc1
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InChI
InChI=1S/C23H27FN6O2/c1-2-4-19-20(32-22(28-19)17-5-7-18(24)8-6-17)21(31)25-11-12-29-13-15-30(16-14-29)23-26-9-3-10-27-23/h3,5-10H,2,4,11-16H2,1H3,(H,25,31)
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InChIKey
VBLZZEZAMDMOAN-UHFFFAOYSA-N
Physicochemical Property
logP
2.7752
Rotatable Bonds
8
Heavy Atom Count
32
Polar Areas
87.39
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46232001
ChEMBL ID
CHEMBL599738
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05900, P2X purinoceptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 10000 nM
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