General Information of the Protein
Protein ID
PT05900
Protein Name
P2X purinoceptor 3
Secondarily
Protein Name
ATP receptor
Purinergic receptor
Gene Name
P2RX3
Sequence
MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDSQCGPERFPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEEVTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH
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Organism
Rattus norvegicus, Rat
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Function
Receptor for ATP that acts as a ligand-gated cation channel (PubMed:7566120, PubMed:7566119). Plays a role in sensory perception. Required for normal perception of pain. Required for normal taste perception (By similarity).
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Uniprot ID
P49654
Ensembl ID
ENSG00000109991
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0001282
 Compound Info 
2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-ylamino)propane-1,3-diol
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C17H23IN4O4
  1
1
IC50 = 1.995 nM
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CP0002141
 Compound Info 
2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propan-1-ol
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C17H23IN4O3
  1
1
IC50 = 6.31 nM
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CP0006445
 Compound Info 
2-[[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]methyl]propane-1,3-diol
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C18H25IN4O4
  1
1
IC50 = 6.31 nM
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CP0003207
 Compound Info 
5-(5-ethynyl-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C16H18N4O2
  1
1
IC50 = 6.31 nM
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CP0003782
 Compound Info 
3-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propane-1,2-diol
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C17H23IN4O4
  1
1
IC50 = 7.943 nM
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CP0005157
 Compound Info 
2-[[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]methyl]-2-methylpropane-1,3-diol
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C19H27IN4O4
  1
1
IC50 = 10 nM
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CP0006675
 Compound Info 
N-[2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]ethyl]acetamide
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C18H24IN5O3
  1
1
IC50 = 10 nM
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CP0007465
 Compound Info 
2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]ethanol
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C16H21IN4O3
  1
1
IC50 = 10 nM
 Bioactivity Info 
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CP0636704
 Compound Info 
(R)-2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-ylamino)propan-1-ol
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C17H23IN4O3
  1
1
IC50 = 10 nM
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CP0003780
 Compound Info 
5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine
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C14H17IN4O2
  1
1
IC50 = 10 nM
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CP0002922
 Compound Info 
1-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propan-2-ol
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C17H23IN4O3
  1
1
IC50 = 12.59 nM
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CP0002265
 Compound Info 
3-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propan-1-ol
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C17H23IN4O3
  1
1
IC50 = 15.85 nM
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CP0007615
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-methylsulfonylethyl)pyrimidine-2,4-diamine
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C17H23IN4O4S
  1
1
IC50 = 15.85 nM
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CP0007198
 Compound Info 
5-(5-bromo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C14H17BrN4O2
  1
1
IC50 = 19.95 nM
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CP0007632
 Compound Info 
5-(5-chloro-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C14H17ClN4O2
  1
1
IC50 = 25.12 nM
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CP0013426
 Compound Info 
5-(4,5-dimethoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C15H20N4O3
  1
1
IC50 = 25.12 nM
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CP0001134
 Compound Info 
N-[(2R)-1-(4-acetylpiperazin-1-yl)propan-2-yl]-1-methyl-3-phenylthieno[2,3-c]pyrazole-5-carboxamide
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C22H27N5O2S
  1
1
IC50 = 31.62 nM
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CP0002267
 Compound Info 
5-(4-iodo-5-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C14H17IN4O2
  1
1
IC50 = 39.81 nM
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CP0006678
 Compound Info 
5-[4-methoxy-2-propan-2-yl-5-(2H-tetrazol-5-yl)phenoxy]pyrimidine-2,4-diamine
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C15H18N8O2
  1
1
IC50 = 39.81 nM
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CP0389739
 Compound Info 
N-[1-(4-acetylpiperazin-1-yl)propan-2-yl]-1-methyl-3-(4-methylphenyl)thieno[2,3-c]pyrazole-5-carboxamide
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C23H29N5O2S
  1
1
IC50 = 39.81 nM
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CP0389741
 Compound Info 
N-[1-(4-acetylpiperazin-1-yl)propan-2-yl]-3-(2-fluorophenyl)-1-methylthieno[2,3-c]pyrazole-5-carboxamide
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C22H26FN5O2S
  1
1
IC50 = 39.81 nM
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CP0003781
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-methylpyrimidine-2,4-diamine
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C15H19IN4O2
  1
1
IC50 = 50.12 nM
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CP0008080
 Compound Info 
5-(5-ethyl-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C16H22N4O2
  1
1
IC50 = 50.12 nM
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CP0009217
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C24H29FN6O2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0002263
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-piperazin-1-ylethyl)pyrimidine-2,4-diamine
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C20H29IN6O2
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
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CP0006407
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-methoxyethyl)pyrimidine-2,4-diamine
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C17H23IN4O3
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
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CP0373992
 Compound Info 
3-(2-fluorophenyl)-1-methyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide
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C24H26FN7OS
  1
1
IC50 = 63.1 nM
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CP0010908
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2,2,2-trifluoroethyl)pyrimidine-2,4-diamine
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C16H18F3IN4O2
  1
1
IC50 = 79.43 nM
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CP0009620
 Compound Info 
5-(4-bromo-5-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C14H17BrN4O2
  1
1
IC50 = 79.43 nM
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CP0007197
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(1-methylsulfonylpiperidin-4-yl)pyrimidine-2,4-diamine
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C20H28IN5O4S
  1
1
IC50 = 100 nM
 Bioactivity Info 
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CP0009399
 Compound Info 
2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]-2-methylpropan-1-ol
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C18H25IN4O3
  1
1
IC50 = 100 nM
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CP0006401
 Compound Info 
5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzamide
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C15H19N5O3
  1
1
IC50 = 100 nM
 Bioactivity Info 
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CP0006676
 Compound Info 
5-(4-methoxy-5-methyl-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C15H20N4O2
  1
1
IC50 = 100 nM
 Bioactivity Info 
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CP0010724
 Compound Info 
5-(4-methoxy-5-methylsulfonyl-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C15H20N4O4S
  1
1
IC50 = 100 nM
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CP0011040
 Compound Info 
N-[1-(4-ethanethioylpiperazin-1-yl)propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide
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C22H29FN4O2S
  1
1
IC50 = 100 nM
 Bioactivity Info 
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CP0946987
 Compound Info 
N-(1-(4-acetylpiperazin-1-yl)propan-2-yl)-1-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide
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C22H27N5O2S
  1
1
IC50 = 100 nM
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CP0008685
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(oxan-4-yl)pyrimidine-2,4-diamine
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C19H25IN4O3
  1
1
IC50 = 125.89 nM
 Bioactivity Info 
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CP0010727
 Compound Info 
5-[(4,5-dimethoxy-2-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine
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C16H22N4O2
  1
1
IC50 = 125.89 nM
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CP0002875
 Compound Info 
3-(4-fluorophenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide
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C24H26FN5O
  1
1
IC50 = 125.89 nM
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CP0002264
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-morpholin-4-ylethyl)pyrimidine-2,4-diamine
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C20H28IN5O3
  1
1
IC50 = 158.49 nM
 Bioactivity Info 
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CP0011109
 Compound Info 
2-N-[2-(dimethylamino)ethyl]-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C18H26IN5O2
  1
1
IC50 = 158.49 nM
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CP0002268
 Compound Info 
5-(2-ethyl-4,5-dimethoxyphenoxy)pyrimidine-2,4-diamine
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C14H18N4O3
  1
1
IC50 = 158.49 nM
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CP0008691
 Compound Info 
5-[5-(1H-imidazol-2-yl)-4-methoxy-2-propan-2-ylphenoxy]pyrimidine-2,4-diamine
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C17H20N6O2
  1
1
IC50 = 158.49 nM
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CP0009510
 Compound Info 
5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzoic acid
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C15H18N4O4
  1
1
IC50 = 158.49 nM
 Bioactivity Info 
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CP0000203
 Compound Info 
1-methyl-3-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide
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C24H27N7OS
  1
1
IC50 = 199.53 nM
 Bioactivity Info 
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CP0008683
 Compound Info 
2-N-(2-aminoethyl)-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C16H22IN5O2
  1
1
IC50 = 251.19 nM
 Bioactivity Info 
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CP0008684
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine
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C21H30IN5O2
  1
1
IC50 = 251.19 nM
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CP0001205
 Compound Info 
2-phenyl-4-propyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C24H30N6O2
  1
1
IC50 = 251.19 nM
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CP0007630
 Compound Info 
1-[2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]ethyl]piperidin-4-ol
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C21H30IN5O3
  1
1
IC50 = 398.11 nM
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CP0008079
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-4-amine
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C14H16IN3O2
  1
1
IC50 = 398.11 nM
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CP0013425
 Compound Info 
5-(5-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C14H18N4O2
  1
1
IC50 = 398.11 nM
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CP0002874
 Compound Info 
3,5-bis(4-fluorophenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide
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C30H29F2N5O
  1
1
IC50 = 398.11 nM
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CP0007697
 Compound Info 
N-[(2R)-1-(4-acetylpiperazin-1-yl)propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide
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C22H29FN4O3
  1
1
IC50 = 398.11 nM
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CP0002266
 Compound Info 
5-[4-methoxy-2,5-di(propan-2-yl)phenoxy]pyrimidine-2,4-diamine
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C17H24N4O2
  1
1
IC50 = 501.19 nM
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CP0006342
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyrazin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C24H29FN6O2
  1
1
IC50 = 501.19 nM
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CP0010293
 Compound Info 
3-bromo-5-(4-fluorophenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide
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C24H25BrFN5O
  1
1
IC50 = 501.19 nM
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CP0011222
 Compound Info 
3-(4-fluorophenyl)-5-propyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]benzamide
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C27H32FN5O
  1
1
IC50 = 501.19 nM
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CP0373993
 Compound Info 
1-ethyl-3-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide
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C25H29N7OS
  1
1
IC50 = 501.19 nM
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CP0001343
 Compound Info 
5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzonitrile
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C15H17N5O2
  1
1
IC50 = 630.96 nM
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CP0007696
 Compound Info 
3,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]furan-2-carboxamide
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C28H29N5O2
  1
1
IC50 = 630.96 nM
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CP0012308
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[1-[4-(1,3-thiazol-2-yl)piperazin-1-yl]propan-2-yl]-1,3-oxazole-5-carboxamide
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C23H28FN5O2S
  1
1
IC50 = 630.96 nM
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CP0006400
 Compound Info 
5-(4-methoxy-5-phenyl-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C20H22N4O2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0001200
 Compound Info 
N-[(2R)-1-(4-carbamoylpiperazin-1-yl)propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide
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C21H28FN5O3
  1
1
IC50 = 1000 nM
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CP0009818
 Compound Info 
1,3-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-4-carboxamide
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C27H29N7O
  1
1
IC50 = 1000 nM
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CP0011037
 Compound Info 
2,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-3-carboxamide
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C27H29N7O
  1
1
IC50 = 1000 nM
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CP0008689
 Compound Info 
5-[(2-cyclopropyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
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C16H20N4O2
  1
1
IC50 = 1258.93 nM
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CP0000417
 Compound Info 
2,4-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C27H28N6O2
  1
1
IC50 = 1258.93 nM
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CP0006779
 Compound Info 
1,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-3-carboxamide
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C27H29N7O
  1
1
IC50 = 1258.93 nM
 Bioactivity Info 
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CP0009821
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyrimidin-4-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C24H29FN6O2
  1
1
IC50 = 1258.93 nM
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CP0011039
 Compound Info 
2,6-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyridine-4-carboxamide
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C29H30N6O
  1
1
IC50 = 1258.93 nM
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CP0002272
 Compound Info 
5-[(2-ethyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
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C15H20N4O2
  1
1
IC50 = 1584.89 nM
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CP0010387
 Compound Info 
5-(4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C14H18N4O2
  1
1
IC50 = 1584.89 nM
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CP0005543
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyridin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C25H30FN5O2
  1
1
IC50 = 1584.89 nM
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CP0003510
 Compound Info 
2,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]furan-3-carboxamide
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C28H29N5O2
  1
1
IC50 = 1995.26 nM
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CP0009819
 Compound Info 
2-methyl-1,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrrole-3-carboxamide
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C29H32N6O
  1
1
IC50 = 1995.26 nM
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CP0012307
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[(2S)-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C24H29FN6O2
  1
1
IC50 = 1995.26 nM
 Bioactivity Info 
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CP0510593
 Compound Info 
1-methyl-3-(2-methylphenyl)-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide
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C25H29N7OS
  1
1
IC50 = 1995.26 nM
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CP0008873
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-methylpyrimidin-4-amine
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C15H18IN3O2
  1
1
IC50 = 2511.89 nM
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CP0007631
 Compound Info 
5-[4-(4-fluorophenyl)-5-methoxy-2-propan-2-ylphenoxy]pyrimidine-2,4-diamine
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C20H21FN4O2
  1
1
IC50 = 2511.89 nM
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CP0000318
 Compound Info 
2-(4-fluorophenyl)-N-[(2R)-1-[4-(furan-2-carbonyl)piperazin-1-yl]propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide
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C25H29FN4O4
  1
1
IC50 = 2511.89 nM
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CP0469700
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[1-(4-pyrimidin-2-yl-1,4-diazepan-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C25H31FN6O2
  1
1
IC50 = 2511.89 nM
 Bioactivity Info 
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CP0011128
 Compound Info 
5-(5-fluoro-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C14H17FN4O2
  1
1
IC50 = 3162.28 nM
 Bioactivity Info 
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CP0008687
 Compound Info 
5-(2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
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C13H16N4O
  1
1
IC50 = 3981.07 nM
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CP0001536
 Compound Info 
2,5-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-4-carboxamide
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C27H28N6O2
  1
1
IC50 = 3981.07 nM
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CP0007318
 Compound Info 
4,6-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrimidine-2-carboxamide
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C28H29N7O
  1
1
IC50 = 5011.87 nM
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CP0009820
 Compound Info 
4-methyl-2-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C22H26N6O2
  1
1
IC50 = 5011.87 nM
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CP0010726
 Compound Info 
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)-2-N,2-N-dimethylpyrimidine-2,4-diamine
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C16H21IN4O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0002269
 Compound Info 
5-[2-(2-ethyl-4,5-dimethoxyphenyl)ethyl]pyrimidine-2,4-diamine
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C16H22N4O2
  1
1
IC50 > 10000 nM
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CP0002270
 Compound Info 
(2,4-diaminopyrimidin-5-yl)-(4,5-dimethoxy-2-propan-2-ylphenyl)methanol
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C16H22N4O3
  1
1
IC50 > 10000 nM
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CP0002271
 Compound Info 
5-[(2-cyclobutyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
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C17H22N4O2
  1
1
IC50 > 10000 nM
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CP0002322
 Compound Info 
4-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-5-propan-2-ylbenzonitrile
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C15H17N5O2
  1
1
IC50 > 10000 nM
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CP0003924
 Compound Info 
5-[(2-tert-butyl-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
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C17H24N4O2
  1
1
IC50 > 10000 nM
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CP0006677
 Compound Info 
(2,4-diaminopyrimidin-5-yl)-(4,5-dimethoxy-2-propan-2-ylphenyl)methanone
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C16H20N4O3
  1
1
IC50 > 10000 nM
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CP0008688
 Compound Info 
5-[[4,5-dimethoxy-2-(2-methylpropyl)phenyl]methyl]pyrimidine-2,4-diamine
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C17H24N4O2
  1
1
IC50 > 10000 nM
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CP0009664
 Compound Info 
ORMETOPRIM
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C14H18N4O2
  1
1
IC50 > 10000 nM
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CP0010725
 Compound Info 
5-[5-(4,5-dihydro-1H-imidazol-2-yl)-4-methoxy-2-propan-2-ylphenoxy]pyrimidine-2,4-diamine
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C17H22N6O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0013427
 Compound Info 
5-[(4,5-dimethoxy-2-propylphenyl)methyl]pyrimidine-2,4-diamine
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C16H22N4O2
  1
1
IC50 > 10000 nM
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CP0002876
 Compound Info 
N-[(2R)-1-[4-(cyclopropanecarbonyl)piperazin-1-yl]propan-2-yl]-2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carboxamide
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C24H31FN4O3
  1
1
IC50 > 10000 nM
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CP0003360
 Compound Info 
2-(4-fluorophenyl)-N-[(2R)-1-[4-(methylcarbamoyl)piperazin-1-yl]propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide
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C22H30FN5O3
  1
1
IC50 > 10000 nM
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CP0003511
 Compound Info 
2,4-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-thiazole-5-carboxamide
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C27H28N6OS
  1
1
IC50 > 10000 nM
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CP0004300
 Compound Info 
2-(4-fluorophenyl)-N-[(2R)-1-(4-methylsulfonylpiperazin-1-yl)propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide
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C21H29FN4O4S
  1
1
IC50 > 10000 nM
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CP0006780
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[1-(4-pyridin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C25H30FN5O2
  1
1
IC50 > 10000 nM
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CP0009822
 Compound Info 
ethyl 4-[(2R)-2-[[2-(4-fluorophenyl)-4-propyl-1,3-oxazole-5-carbonyl]amino]propyl]piperazine-1-carboxylate
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C23H31FN4O4
  1
1
IC50 > 10000 nM
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CP0011038
 Compound Info 
5-methyl-1,3-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]pyrazole-4-carboxamide
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C28H31N7O
  1
1
IC50 > 10000 nM
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CP0011223
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[(2R)-1-(4-pyridin-4-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamide
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C25H30FN5O2
  1
1
IC50 > 10000 nM
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CP0373994
 Compound Info 
1,3-diphenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide
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C29H29N7OS
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0376360
 Compound Info 
2-(4-fluorophenyl)-N-[2-methyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide
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C25H31FN6O2
  1
1
IC50 > 10000 nM
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CP0376361
 Compound Info 
1-(4-fluorophenyl)-3-phenyl-5-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-6H-pyrrolo[3,4-c]pyrazol-4-one
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C28H28FN7O
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0384439
 Compound Info 
1-methyl-3-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]furo[2,3-c]pyrazole-5-carboxamide
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C24H27N7O2
  1
1
IC50 > 10000 nM
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CP0417944
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]-1,3-oxazole-5-carboxamide
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C23H27FN6O2
  1
1
IC50 > 10000 nM
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CP0469701
 Compound Info 
2-(4-fluorophenyl)-4-propyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)butan-2-yl]-1,3-oxazole-5-carboxamide
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C25H31FN6O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0469860
 Compound Info 
2-(4-fluorophenyl)-N-methyl-4-propyl-N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]-1,3-oxazole-5-carboxamide
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C24H29FN6O2
  1
1
IC50 > 10000 nM
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CP0469861
 Compound Info 
2-(4-fluorophenyl)-4-propyl-5-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yloxymethyl]-1,3-oxazole
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C24H30FN5O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0504727
 Compound Info 
3-methyl-1-phenyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]thieno[2,3-c]pyrazole-5-carboxamide
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C24H27N7OS
  1
1
IC50 = 10000 nM
 Bioactivity Info 
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CP0522013
 Compound Info 
N-[[2-(4-fluorophenyl)-4-propyl-1,3-oxazol-5-yl]methyl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-amine
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C24H31FN6O
  1
1
IC50 > 10000 nM
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Cell Line ID: CL000026 , CHO-K1
 Cell Line Info