General Information of the Compound
Compound ID
CP0004300
Compound Name
2-(4-fluorophenyl)-N-[(2R)-1-(4-methylsulfonylpiperazin-1-yl)propan-2-yl]-4-propyl-1,3-oxazole-5-carboxamide
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Structure
Formula
C21H29FN4O4S
Molecular Weight
452.552
Canonical SMILES
CCCc1nc(oc1C(=O)N[C@H](C)CN1CCN(CC1)S(C)(=O)=O)-c1ccc(F)cc1
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InChI
InChI=1S/C21H29FN4O4S/c1-4-5-18-19(30-21(24-18)16-6-8-17(22)9-7-16)20(27)23-15(2)14-25-10-12-26(13-11-25)31(3,28)29/h6-9,15H,4-5,10-14H2,1-3H3,(H,23,27)/t15-/m1/s1
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InChIKey
CGVOTXJTJPDUMN-OAHLLOKOSA-N
Physicochemical Property
logP
2.1287
Rotatable Bonds
8
Heavy Atom Count
31
Polar Areas
95.75
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46231791
ChEMBL ID
CHEMBL604938
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05900, P2X purinoceptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS